Lim homeobox 9

LIM homeobox 9 is a protein that in humans is encoded by the LHX9 gene.[5]

LHX9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesLHX9, LIM homeobox 9
External IDsOMIM: 606066 MGI: 1316721 HomoloGene: 7816 GeneCards: LHX9
Orthologs
SpeciesHumanMouse
Entrez

56956

16876

Ensembl

ENSG00000143355

ENSMUSG00000019230

UniProt

Q9NQ69

Q9WUH2

RefSeq (mRNA)

NM_001014434
NM_020204
NM_001370213

NM_001025565
NM_001042577
NM_010714

RefSeq (protein)

NP_001014434
NP_064589
NP_001357142

NP_001020736
NP_001036042
NP_034844

Location (UCSC)Chr 1: 197.91 – 197.94 MbChr 1: 138.83 – 138.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants.

References

  1. GRCh38: Ensembl release 89: ENSG00000143355 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000019230 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: LIM homeobox 9".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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