Lipoblastoma
Lipoblastoma is a type of rare, subcutaneous, benign, fatty tumor,[1][2] found in infants, and children, more common in males with tendency of local recurrence. Local recurrence can happen in up to 80% of incompletely resected tumours. Therefore, complete surgical resection is required to prevent recurrence. It arises from embyronic white fat that is rapidly enlarging. Most common locations are at the trunk and extremities.[3]
| Lipoblastoma | |
|---|---|
 | |
| Lipoblastoma. Note the plexiform vascular pattern and small immature adipocytes. | |
| Specialty | Oncology  |
Types include:
- Benign lipoblastomatosis, a tumor, also known as an embryonic lipoma, which usually occurs in children under three years old. This is the tumor of brown fat cells.
- Myxoid lipoblastoma, a cutaneous condition characterized by excess mucin
Specimen
Macroscopic
Grossly, it has a pale yellow, myxoid cut surface with small cystic foci.[3]
Microscopic
It has lobules consists of immature adipose tissue separated by fibrous septa and lipoblasts at different stages of maturation, without atypia or mitosis. Plexiform capillary network and mature adipose tissue are seen at the central part of the lobule.[3]
References
- A. M. A. de Schepper; Paul M. Parizel; Filip M. Vanhoenacker (2006). Imaging of soft tissue tumors. Springer. pp. 233–6. ISBN 978-3-540-24809-5. OCLC 181443089.
- Akbar Bonakdar-Pour; William R. Reinus; Jasvir S. Khurana (22 September 2009). Diagnostic Imaging of Musculoskeletal Diseases: A Systematic Approach. Springer. p. 319. ISBN 978-1-58829-947-5. Retrieved 11 March 2011.
- Abdul-Ghafar J, Ahmad Z, Tariq MU, Kayani N, Uddin N (January 2018). "Lipoblastoma: a clinicopathologic review of 23 cases from a major tertiary care center plus detailed review of literature". BMC Research Notes. 11 (1): 42. doi:10.1186/s13104-018-3153-8. PMC 5773143. PMID 29343278.