List of electronic laboratory notebook software packages

An electronic lab notebook (also known as electronic laboratory notebook, or ELN) is a computer program designed to replace paper laboratory notebooks. Lab notebooks in general are used by scientists, engineers, and technicians to document research, experiments, and procedures performed in a laboratory. A lab notebook is often maintained to be a legal document and may be used in a court of law as evidence. Similar to an inventor's notebook, the lab notebook is also often referred to in patent prosecution and intellectual property litigation.

Electronic lab notebooks are a fairly new technology and offer many benefits to the user as well as organizations. For example: electronic lab notebooks are easier to search upon, simplify data copying and backups, and support collaboration amongst many users.[1] ELNs can have fine-grained access controls, and can be more secure than their paper counterparts.[2] They also allow the direct incorporation of data from instruments, replacing the practice of printing out data to be stapled into a paper notebook.[3] This is a list of ELN software packages. It is incomplete, as a recent review listed 96 active & 76 inactive (172 total) ELN products.[4] Notably, this review and other lists of ELN software often do not include widely used generic notetaking software like Onenote, Notion, Jupyter etc, due to their lack ELN nominal features like time-stamping and append-only editing. Some ELNs are web-based; others are used on premise and a few are available for both environments.

ELN Software
Name Developer(s) Initial release Country of origin 21 CFR Part 11 Compliance Information
LabCollector[5] AgileBio 2002 France [6]
Labii[7][8] Labii Inc. 2016[9] United States [10]
Colabra Colabra Inc. 2021[11] United States Paid plans[12]
Scispot Scispot.io Inc. 2021[13][14] Canada
CDD Vault ELN Collaborative Drug Discovery, Inc.  2018[15][16][17] United States
Uncountable Uncountable Inc. 2018[18][19] United States [20]
Signals Notebook PerkinElmer Inc. 2017[21] United States
Pillar Science Pillar Science 2017[22]
Mbook[23] Mestrelab Research 2015[24] Spain
SciNote ELN By SciNote LLC[25] and BioSistemika LLC, based on a later published scientific study[26] 2015 [27] United States [28]
Labstep Labstep 2015[29] United Kingdom [30]
RND NOTE[31] Cyberline Co., Ltd. 2015 South Korea
Open Science Framework (OSF) Center for Open Science 2013[32] United States
Labfolder[23] Labforward GmbH 2012 Germany [33]
RSpace[23] ResearchSpace 2012[34] United States [35]
Benchling[23] Benchling, Inc. 2012 United States [36]
LabGuru Biodata Ltd[37] 2011[37] United States
Scilligence ELN[38] Scilligence 2011 United States [39]
Arxspan ELN Bruker, Inc.  2011[40][41] United States [42]
eLabJournal[23] eLabNext 2010 The Netherlands [43]
LabArchives LabArchives LLC 2009[44] United States [45]
Sapio Seamless ELN Sapio Sciences LLC 2007[46] United States
LabWare LabWare ELN 2010[47] United States [48]
Sapio Seamless ELN Sapio Sciences LLC 2007[49] United States
LabVantage 8 LabVantage Solutions, Inc. 2007[50] United States [51]

Open-source ELN software
ELN software Language base License Hosted on Other info
Jupyter Python BSD Personal computer or server Web application[52]
OpenWetWare PHP GPL v2 MIT
elabFTW PHP GNU AGPLv3 Personal computer or server Developed at Curie Institute, Paris[53]
OpenBIS Java, Python Apache License 2.0 Personal computer or server Developed at ETH Zürich

References
  1. Myers J, Mendoza E, Hoopes B (2001). A Collaborative Electronic Notebook. Proceedings of the IASTED International Conference on Internet and Multimedia Systems and Applications.
  2. Myers J (2003). Collaborative Electronic Notebooks as Electronic Records:Design Issues for the Secure Electronic Laboratory Notebook (ELN) (PDF). Proceedings of the 2003 International Symposium on Collaborative Technologies and Systems. Archived from the original (PDF) on 2011-10-15. Retrieved 2017-11-14.
  3. Perkel JM (June 2011). "Coding your way out of a problem". Nature Methods. 8 (7): 541–3. doi:10.1038/nmeth.1631. PMID 21716280. S2CID 13175560.
  4. Higgins, Stuart G.; Nogiwa-Valdez, Akemi A.; Stevens, Molly M. (2022-01-14). "Considerations for implementing electronic laboratory notebooks in an academic research environment". Nature Protocols. Springer Science and Business Media LLC. 17 (2): 179–189. doi:10.1038/s41596-021-00645-8. ISSN 1754-2189. PMID 35031789. S2CID 245965212.
  5. "LabCollector - All-in-one Lab Notebook and Management Platform _ Free LIMS". LabCollector. Retrieved 2023-08-24.
  6. "LabCollector LIMS & Regulatory Compliance". LabCollector. Retrieved 2023-08-24.
  7. "Global Electronic Laboratory Notebooks (ELNs) Market Trajectory & Analytics 2021-2027, Featuring Abbott Informatics, Benchling, Labii Inc., SciNote LLC. and More". www.yahoo.com. Retrieved 2022-02-08.
  8. "2021 Review of the Best Electronic Laboratory Notebooks | Labs Explorer". www.labsexplorer.com. Retrieved 2022-02-08.
  9. "Labii will now offer ELN & LIMS to all MBC BioLabs startups". BioSpace. Retrieved 2022-02-08.
  10. "Labii Regulation". Labii Regulation. Retrieved 2021-02-08.
  11. "Colabra raises $1.5 million for its online and mobile scientific collaboration software". www.eurekalert.org. Retrieved 2021-08-20.
  12. "Pricing". www.colabra.app. Retrieved 2022-01-03.
  13. "Scispot.io launches a no-code digital operating platform for bioentrepreneurs to democratize life science". Wiley Analytical Science.
  14. "Tech lets bioentrepreneurs run start-ups from coffee shops". Drug Discovery World.
  15. "CDD Vault Update: CDD Vault is Now and ELN". Collaborative Drug Discovery Inc.
  16. CDD Electronic Lab Notebook (ELN) - Collaborative Drug Discovery Inc. (CDD)
  17. "Electronic Lab Notebooks: What They Are (And Why You Need One)". Collaborative Drug Discovery Inc.
  18. "Uncountable Web Platform Reviews & Product Details". G2. Retrieved 2020-08-02.
  19. "Streamlining R&D for material formulation". MIT Startup Exchange. Retrieved 2020-08-02.
  20. "Technology - Uncountable". www.uncountable.com. Retrieved 2022-01-03.
  21. "New Cloud-Based PerkinElmer Signals™ Notebook Helps Scientists Accelerate Drug Discovery Research". PerkinElmer, Inc. Retrieved 2020-02-07.
  22. "Pillar Science Pricing, Alternatives & More 2022 - Capterra". www.capterra.com. Retrieved 2022-01-03.
  23. "Best electronic lab notebook review (ELN) for your lab 2021". 2021-05-26. Retrieved 2022-01-03.
  24. "WEBINAR: Mbook Introduction". Mestrelab Resources. 2015-03-31. Retrieved 2021-05-20.
  25. Masa. "SciNote ELN: Electronic Lab Notebook & Inventory Management". SciNote. Retrieved 2020-12-14.
  26. Kanza S, Willoughby C, Gibbins N, Whitby R, Frey JG, Erjavec J, et al. (May 2017). "Electronic lab notebooks: can they replace paper?". Journal of Cheminformatics. 9 (1): 31. doi:10.1186/s13321-017-0221-3. PMC 5443717. PMID 29086051.
  27. Tea. "About Us - SciNote electronic lab notebook - team presentation". SciNote. Retrieved 2020-12-14.
  28. Masa (2020-05-08). "SciNote Solutions: SciNote in regulated GxP environments: GLP, GMP". SciNote. Retrieved 2022-01-03.
  29. "Labstep wants to fix the way science experiments are recorded and reproduced". TechCrunch. Retrieved 2019-01-11.
  30. "Labstep and FDA 21 CFR Part 11 Compliance". help.labstep.com. Retrieved 2022-01-03.
  31. "RndNote (ELN)". LabsExplorer.
  32. "Psychologists Launch a Bare-All Research Initiative - ScienceInsider". 2013-05-11. Archived from the original on 2013-05-11. Retrieved 2020-02-07.
  33. "Does Labfolder meet FDA CFR 21 Part II requirements? - Labfolder". Labforward GmbH. Retrieved 2022-01-03.
  34. "About". ResearchSpace. Retrieved 2022-01-03.
  35. "FAQ". researchspace.helpdocs.io. 2019-07-15. Retrieved 2022-01-03.
  36. "Read Benchling's security documentation". help.benchling.com. Retrieved 2022-01-03.
  37. "BioData Launches Labguru, a Collaborative Research Management Web Application for Academic Labs - Technology for Researchers". 2012-05-10. Archived from the original on 2012-05-10. Retrieved 2020-02-07.
  38. "Scilligence and TetraScience Announce Integration Plan to Automate Research Data". PR Newswire. Retrieved 2020-03-10.
  39. "Electronic Lab Notebook | Scilligence". 2016-06-06. Retrieved 2022-01-03.
  40. "Arxspan Notebook - ELN". Arxspan.
  41. "Bruker Announces Acquisition of Scientific Software Provider Arxspan". Bruker.
  42. "Arxspan - Prompt, Around The Clock Support". Arxspan. Retrieved 2022-01-03.
  43. "Compliance Archives". eLabNext. Retrieved 2022-01-03.
  44. TachibanaJul C (2014-07-25). "The paperless lab". Science | AAAS. Retrieved 2020-02-07.
  45. "FAQs". LabArchives. Retrieved 2022-01-03.
  46. "ChemAxon partners - Sapio Sciences".
  47. LabWare (2010-03-01). "LabWare ELN" (PDF).
  48. "How the Best LIMS Software Can Help Your Lab Compliance". LabWare. Retrieved 2023-01-09.
  49. "ChemAxon partners - Sapio Sciences".
  50. "eNotebook - LabVantage Solutions". 2019-03-03. Archived from the original on 2019-03-03. Retrieved 2020-02-07.
  51. Solutions, LabVantage (2018-06-15). "LIMS and FDA 21 CFR Part 11 Compliance". LabVantage. Retrieved 2022-01-03.
  52. "The IPython Notebook — IPython 2.3.0 documentation". 2015-01-02. Archived from the original on 2015-01-02. Retrieved 2018-06-28.
  53. "Biostars". 2014-09-10. Retrieved 2019-12-10.
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