Live birth (human)

In human reproduction, a live birth occurs when a fetus exits the mother showing any definite sign of life such as voluntary movement, heartbeat, or pulsation of the umbilical cord, for however brief a time and regardless of whether the umbilical cord or placenta are intact.[1] After the fetus is expelled from the maternal body it is called a neonate. Whether the birth is vaginal or by Caesarean section, and whether the neonate is ultimately viable, is irrelevant.

For organisms where the embryo develops inside the mother as opposed to an egg, see viviparity.

The definition of the term "live birth" was created by the World Health Organization in 1950, and is chiefly used for public health and statistical purposes. However, the term "live birth" was in common use long before 1950.[2]

In the United States, the term "born alive" is defined by federal law[3] known as the born alive rule. Live births are recorded on a U.S. Standard Certificate of Live Birth, also known as a birth certificate.[4] The United States recorded 3,605,201 live births in 2020 which is a 4% decrease from 2019 and the 6th consecutive year of decline in births.[5]

Not all pregnancies result in live births. A woman may choose to end her pregnancy by abortion. Miscarriage, also known as spontaneous abortion and pregnancy loss, is the natural death of an embryo or fetus before it is able to survive independently.[6][7] Some use the cutoff of 20 weeks of gestation, after which fetal death is known as a stillbirth.[8] The death of the fetus or neonate at the end of the pregnancy, during labour and delivery, or just after birth is counted as perinatal mortality.

Factors affecting viability

Gestational age

Measured in weeks, gestational age is a term used to describe how far along a pregnancy is starting from the first day of the woman's last menstrual cycle to the current date.[9] A baby born "at term" is between the gestational age of 37 weeks to 41 weeks. A preterm baby is born before the gestational age of 37 weeks. A pregnancy that lasts 41 weeks up to 42 weeks is called late-term and a pregnancy longer than 42 weeks is called post-term.[10] The general consensus is that a fetus is viable at 24 weeks, however, a live birth may occur earlier in gestation with the assistance from neonatal intensive care unit (NICU) resources. Gestational age is the main determinant of whether a baby will be able to live and survive outside of the uterus.

Other factors

While gestational age is the most significant predictor of fetal viability, the condition of the neonate at birth also significantly indicates how well it tolerates life outside of the mother. Factors measured at birth include birth weight, head circumference, and body length. An Apgar score is given at the time of birth to report the status of the newborn infant and the response to resuscitation if needed.[11]

Recovery

The maternal recovery period directly following the events of human childbirth, regardless of whether it is a live birth, is called the postpartum period.

Special cases

There is one case report of a woman having a live birth derived from a frozen embryo obtained before she began cancer treatment.[12]

See also

References
  1. World Health Organization. International statistical classification of diseases and related health problems. Tenth Revision. Vol 2. Geneva, Switzerland: World Health Organization, 1993:129.
  2. Search full view Google Books for "live birth" prior to the year 1950.
  3. "1 U.S. Code § 8 - "Person", "human being", "child", and "individual" as including born-alive infant". LII / Legal Information Institute. Retrieved 22 August 2017.
  4. "NVSS - Revisions of the U.S. Standard Certificates and Reports". www.cdc.gov. 2017-08-30. Retrieved 2018-10-23.
  5. Hamilton, Brady; Martin, Joyce; Osterman, Michelle (May 2021). "Births: Provisional Data for 2020" (PDF). Division of Vital Statistics, National Center for Health Statistics. Vital Statistics Rapid Release. National Vital Statistics System. Report No. 012 – via CDC.
  6. The Johns Hopkins Manual of Gynecology and Obstetrics (4 ed.). Lippincott Williams & Wilkins. 2012. pp. 438–439. ISBN 9781451148015. Archived from the original on September 10, 2017.
  7. "What is pregnancy loss/miscarriage?". www.nichd.nih.gov/. July 15, 2013. Archived from the original on April 2, 2015. Retrieved March 14, 2015.
  8. "Stillbirth: Overview". NICHD. September 23, 2014. Archived from the original on October 5, 2016. Retrieved October 4, 2016.
  9. "Gestational age: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2022-06-23.
  10. "When Pregnancy Goes Past Your Due Date". www.acog.org. Retrieved 2022-06-23.
  11. "The Apgar Score". www.acog.org. Retrieved 2022-06-25.
  12. Yang, Dunsong; Brown, Samuel E.; Nguyen, Kevin; Reddy, Vijay; Brubaker, Cindy; Winslow, Kevin L. (1 June 2007). "Live birth after the transfer of human embryos developed from cryopreserved oocytes harvested before cancer treatment". Fertility and Sterility. 87 (6): 1469.e1–4. doi:10.1016/j.fertnstert.2006.07.1546. PMID 17418837.
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