Proteins produced and secreted by the liver

The liver plays the major role in producing proteins that are secreted into the blood, including major plasma proteins, factors in hemostasis and fibrinolysis, carrier proteins, hormones, prohormones and apolipoprotein:

Major plasma proteins

All plasma proteins except Gamma-globulins are synthesised in the liver.[1]

Factors in hemostasis and fibrinolysis

Carrier proteins

Hormones

Prohormones

  • Angiotensinogen, when converted to angiotensin causes vasoconstriction and release of aldosterone, in effect increasing blood pressure

Apolipoproteins

References

General reference for the list of included substances (but not their functions):

  • Table 45–4 in: Walter F., PhD. Boron (2003). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. p. 1300. ISBN 1-4160-2328-3.

Other:

  1. Miller, L. L.; Bale, W. F. (February 1954). "Synthesis of all plasma protein fractions except gamma globulins by the liver; the use of zone electrophoresis and lysine-epsilon-C14 to define the plasma proteins synthesized by the isolated perfused liver". The Journal of Experimental Medicine. 99 (2): 125–132. doi:10.1084/jem.99.2.125. ISSN 0022-1007. PMC 2180344. PMID 13130789.
  2. Lippincott's Illustrated Reviews: Immunology. Paperback: 384 pages. Publisher: Lippincott Williams & Wilkins; (July 1, 2007). Language: English. ISBN 978-0-7817-9543-2. Page 182
  3. BRS Pathology 5th Edition, pg. 196
  4. Robbins Basic Pathology 9th Edition, Chapter 11
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