Lysophosphatidylserine

Lysophosphatidylserine is a lysophospholipid which triggers TLR 2.

A recent study showed that it does not stimulate normal leukocytes.[1] It also enhances glucose transport, lowering blood glucose levels while leaving secretion of insulin unaffected.[2]

References

Park KS, Lee HY, Kim MK, Shin EH, Bae YS (Jul 2005). "Lysophosphatidylserine stimulates leukemic cells but not normal leukocytes". Biochemical and Biophysical Research Communications. 333 (2): 353–8. doi:10.1016/j.bbrc.2005.05.109. PMID 15946646.
Yea K, Kim J, Lim S, Kwon T, Park HS, Park KS, Suh PG, Ryu SH (Jan 2009). "Lysophosphatidylserine regulates blood glucose by enhancing glucose transport in myotubes and adipocytes". Biochemical and Biophysical Research Communications. 378 (4): 783–8. doi:10.1016/j.bbrc.2008.11.122. PMID 19063864.

External links

Lysophosphatidylserine at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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[pmid15946646-1] Park KS, Lee HY, Kim MK, Shin EH, Bae YS (Jul 2005). "Lysophosphatidylserine stimulates leukemic cells but not normal leukocytes". Biochemical and Biophysical Research Communications. 333 (2): 353–8. doi:10.1016/j.bbrc.2005.05.109. PMID 15946646.

[2] Yea K, Kim J, Lim S, Kwon T, Park HS, Park KS, Suh PG, Ryu SH (Jan 2009). "Lysophosphatidylserine regulates blood glucose by enhancing glucose transport in myotubes and adipocytes". Biochemical and Biophysical Research Communications. 378 (4): 783–8. doi:10.1016/j.bbrc.2008.11.122. PMID 19063864.