M. Madan Babu

M. Madan Babu FRS FRSC FMedSci is an Indian-American computational biologist and bioinformatician.[1][3] He is the endowed chair in biological data science and director of the center of excellence for data-driven discovery at St. Jude Children’s Research Hospital. Previously, he served as a programme leader at the MRC Laboratory of Molecular Biology (LMB).[4]

M. Madan Babu

FRS FRSC FMedSci
M. Madan Babu speaking at the Intelligent Systems for Molecular Biology (ISMB) conference in Chicago in 2018
Born
Mohan Madan Babu
Alma materAnna University (BTech)
University of Cambridge (PhD)
Awards
Scientific career
FieldsComputational biology
Systems biology
Network biology
Disordered proteins
Regulatory genomics[1]
InstitutionsSt. Jude Children's Research Hospital
MRC Laboratory of Molecular Biology
University of Cambridge
National Center for Biotechnology Information
ThesisEvolution of transcriptional regulatory networks (2004)
Doctoral advisorSarah Teichmann[2]
Websitewww.stjude.org/directory/b/madan-babu.html

Early life and education

Babu grew up in Chennai, India.[5] He became interested in learning to program as a young child when his father brought home a personal computer.[5] Babu was introduced to biotechnology as a high school student.[5] He obtained his Bachelor of Technology degree from Anna University, where he was introduced to the field of computational biology.[5] Babu obtained his PhD in computational genomics at the University of Cambridge supervised by Sarah Teichmann in 2004.[2]

Career and research

After his PhD, Babu was a postdoctoral researcher at the National Center for Biotechnology Information (NCBI), at the National Institute of Health (NIH) in Bethesda, Maryland with Aravind L. Iyer. In 2006, he became a group leader at the MRC Laboratory of Molecular Biology in Cambridge, UK. In July 2020, Babu joined the faculty of St. Jude Children’s Research Hospital as the endowed chair in biological data science in the structural biology department and director of the center of excellence for data-driven discovery.[6]

Babu's research focuses on understanding the regulation of cellular systems at varying scales, including molecular, system, and genomic levels.[1] He also studies the effects of such regulation on genome evolution.[5][7] In particular, his research group studies G protein-coupled receptors and intrinsically disordered proteins using a combination of computational biology and experimental biology approaches.[8][9]

As of 2020 Babu serves as chief editor of the journal Molecular Systems Biology.[7][10]

Awards and honours

References
  1. M. Madan Babu publications indexed by Google Scholar
  2. Mohan, Madan Babu (2004). Evolution of transcriptional regulatory networks. cam.ac.uk (PhD thesis). University of Cambridge. OCLC 890159758. EThOS uk.bl.ethos.616113.
  3. M. Madan Babu publications from Europe PubMed Central
  4. Various (2005). "The Transcriptional Landscape of the Mammalian Genome". Science. 309 (5740): 1559–1563. Bibcode:2005Sci...309.1559F. doi:10.1126/science.1112014. ISSN 0036-8075. PMID 16141072. S2CID 8712839.
  5. "2018 ISCB Innovator Award: M. Madan Babu". iscb.org. Retrieved 21 November 2020.
  6. "M. Madan Babu joins St. Jude Children's Research Hospital as endowed chair in biological data science". stjude.org. Retrieved 21 November 2020.
  7. Kiessling, Tilmann (2019). "Molecular Systems Biology appoints M. Madan Babu as new Chief Editor". embo.org. Retrieved 22 November 2020.
  8. Patterson, Holly (29 November 2016). "Code-cracking: using computers to understand life's source codes". Inside Science.
  9. Anon (2016). "Illuminating the Dark Proteome". Cell. 166 (5): 1074–1077. doi:10.1016/j.cell.2016.08.012. ISSN 0092-8674. PMID 27565336.
  10. Lemberger, Thomas; Babu, M Madan (2019). "Enabling next generation systems biology: a conversation with M. Madan Babu". Molecular Systems Biology. 15 (12): e9376. doi:10.15252/msb.199376. ISSN 1744-4292. PMC 6894041. PMID 31885204.
  11. "EMBO recognizes talented young group leaders in Europe" (PDF). ifom.eu. 4 November 2009.
  12. "Biochemical Society 2010 Award Winners".
  13. "Genetics Society Balfour Lecture".
  14. "Royal Society of Chemistry Molecular BioSystems Award 2011". Molecular BioSystems. 7 (2): 281. 2011. doi:10.1039/C0MB90043E.
  15. "The Colworth Medal". biochemistry.org.
  16. "Melina Schuh and M. Madan Babu awarded Lister Research Prizes". mrc-lmb.cam.ac.uk. MRC Laboratory of Molecular Biology. 3 September 2014. Retrieved 21 November 2020.
  17. "Madan Babu Archives".
  18. "The Protein Society announces its 2014 award recipients". EurekAlert!. Retrieved 13 April 2021.
  19. Anon (2015). "Unstructured proteins: cellular complexity and human diseases". royalsociety.org. London: Royal Society. Retrieved 21 November 2020.
  20. "Three LMB scientists elected to EMBO membership". mrc-lmb.cam.ac.uk. MRC Laboratory of Molecular Biology. 23 May 2016. Retrieved 21 November 2020.
  21. "The United Kingdom's Top Scientists and Engineers Honoured by the Inaugural Blavatnik Awards for Young Scientists". blavatnikawards.org. Blavatnik Awards for Young Scientists. Retrieved 22 November 2020.
  22. Fogg, Christiana N.; Kovats, Diane E.; Shamir, Ron (2018). "2018 ISCB Innovator Award recognizes M. Madan Babu". PLOS Computational Biology. 14 (6): e1006164. Bibcode:2018PLSCB..14E6164F. doi:10.1371/journal.pcbi.1006164. ISSN 1553-7358. PMC 5991638. PMID 29879101.
  23. Kiessling, Tilmann (2019). "M. Madan Babu and Paola Picotti honoured with EMBO Gold Medal". embo.org. Retrieved 21 November 2020.
  24. "50 outstanding biomedical and health scientists elected to prestigious Academy of Medical Sciences Fellowship | The Academy of Medical Sciences". acmedsci.ac.uk. Retrieved 16 May 2021.
  25. "Madan Babu Mohan". The Royal Society. Retrieved 25 May 2023.
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