MFSD7

SLC49A3
Identifiers
Aliases	SLC49A3, LP2561, major facilitator superfamily domain containing 7, solute carrier family 49 member 3, MFSD7
External IDs	MGI: 2442629 HomoloGene: 49990 GeneCards: SLC49A3
Gene location (Human)
Chr.	Chromosome 4 (human)[1]
End	689,441 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	108,596,966 bp[2]
RNA expression pattern
	Top expressed in
	monocyte; ; right lobe of thyroid gland; ; minor salivary gland; ; left lobe of thyroid gland; ; body of stomach; ; skin of abdomen; ; upper lobe of left lung; ; spleen; ; right lung; ; ascending aorta;
	Top expressed in
	white adipose tissue; ; zone of skin; ; colon; ; lip; ; ileum; ; esophagus; ; jejunum; ; duodenum; ; urinary bladder; ; muscle tissue;
	More reference expression data
	n/a
Orthologs
	84179
	243197
	ENSG00000169026
	ENSMUSG00000029490
	Q6UXD7
	Q8CE47
	NM_001294341; NM_001294342; NM_032219
	NM_172883; NM_001359977
NP_001281270; NP_001281271; NP_115595; NP_001364988; NP_001364989;
	NP_001364990; NP_001364991
	NP_766471; NP_001346906
	Wikidata
View/Edit Human	View/Edit Mouse

Major facilitator superfamily domain containing 7 is a protein that in humans is encoded by the MFSD7 gene.[5]

MFSD7is an atypical SLC,[6][7] thus a predicted SLC transporter. It clusters phylogenetically to the Atypical MFS Transporter family 5(AMTF5) and the SLC49 family.

References

GRCh38: Ensembl release 89: ENSG00000169026 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000029490 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Major facilitator superfamily domain containing 7".
Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.
Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000169026 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029490 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Major facilitator superfamily domain containing 7".

[6] Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.

[7] Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.