Major facilitator superfamily domain-containing protein 9

MFSD9
Identifiers
Aliases	MFSD9, major facilitator superfamily domain containing 9
External IDs	MGI: 2443548 HomoloGene: 13100 GeneCards: MFSD9
Gene location (Human)
Chr.	Chromosome 2 (human)[1]
End	102,736,888 bp[1]
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)[2]
End	40,829,847 bp[2]
RNA expression pattern
	Top expressed in
	body of pancreas; ; rectum; ; jejunal mucosa; ; right lobe of liver; ; bone marrow cells; ; duodenum; ; endothelial cell; ; ganglionic eminence; ; islet of Langerhans; ; body of stomach;
	Top expressed in
	secondary oocyte; ; jejunum; ; proximal tubule; ; prostate; ; ileum; ; kidney; ; large intestine; ; colon; ; left colon; ; duodenum;
	More reference expression data
	n/a
Gene ontology
Molecular function	transporter activity;
Cellular component	membrane; integral component of membrane;
Biological process	transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	84804
	211798
	ENSG00000135953
	ENSMUSG00000041945
	Q8NBP5
	Q8C0T7
	NM_032718; NM_001322080; NM_001322081
	NM_172499
	NP_001309009; NP_001309010; NP_116107
	NP_766087
	Wikidata
View/Edit Human	View/Edit Mouse

Major facilitator superfamily domain-containing protein 9 is a protein that in humans is encoded by the MFSD9 gene. It is a potential solute carrier, and called atypical solute carrier[5] since it is not named according to the SLC nomenclature.[6] It is expressed both in central and peripheral organs.[7]

References

GRCh38: Ensembl release 89: ENSG00000135953 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000041945 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.
Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.
Perland E, Hellsten SV, Schweizer N, Arapi V, Rezayee F, Bushra M, Fredriksson R (2017). "Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice". PLOS ONE. 12 (10): e0186325. Bibcode:2017PLoSO..1286325P. doi:10.1371/journal.pone.0186325. PMC 5648162. PMID 29049335.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135953 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041945 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.

[6] Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.

[7] Perland E, Hellsten SV, Schweizer N, Arapi V, Rezayee F, Bushra M, Fredriksson R (2017). "Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice". PLOS ONE. 12 (10): e0186325. Bibcode:2017PLoSO..1286325P. doi:10.1371/journal.pone.0186325. PMC 5648162. PMID 29049335.