MIR1269A

MIR1269A
Identifiers
Aliases	MIR1269A, MIR1269, MIRN1269, hsa-mir-1269, hsa-mir-1269a, microRNA 1269a
External IDs	GeneCards: MIR1269A
Gene location (Human)
Chr.	Chromosome 4 (human)[1]
End	66,276,928 bp[1]
RNA expression pattern
	Top expressed in
	right lobe of liver; ; gastrocnemius muscle; ; blood; ; thoracic aorta; ; ascending aorta; ; subcutaneous adipose tissue; ; dorsolateral prefrontal cortex; ; nucleus accumbens; ; skin of abdomen; ; tibial nerve;
	n/a
	More reference expression data
	n/a
Orthologs
	100302177
	n/a
	ENSG00000221563
	n/a
	n; a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

MicroRNA 1269a is a protein that in humans is encoded by the MIR1269A gene. [3]

Function

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].

References

GRCh38: Ensembl release 89: ENSG00000221563 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: MicroRNA 1269a". Retrieved 2013-12-19.

MIR1269A

Function

References

Further reading