MPDZ

Multiple PDZ domain protein is a protein that in humans is encoded by the MPDZ gene.[5]

MPDZ
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMPDZ, HYC2, MUPP1, multiple PDZ domain crumbs cell polarity complex component
External IDsOMIM: 603785 MGI: 1343489 HomoloGene: 2841 GeneCards: MPDZ
Orthologs
SpeciesHumanMouse
Entrez

8777

17475

Ensembl

ENSG00000107186

ENSMUSG00000028402

UniProt

O75970

Q8VBX6

RefSeq (mRNA)

NM_001261406
NM_001261407
NM_003829
NM_001330637

NM_010820
NM_001305284
NM_001305286

RefSeq (protein)

NP_001292213
NP_001292215
NP_034950

Location (UCSC)Chr 9: 13.11 – 13.28 MbChr 4: 81.28 – 81.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

MPDZ has been shown to interact with:

References

  1. GRCh38: Ensembl release 89: ENSG00000107186 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028402 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: MPDZ multiple PDZ domain protein".
  6. Becamel C, Figge A, Poliak S, Dumuis A, Peles E, Bockaert J, Lubbert H, Ullmer C (April 2001). "Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1". J. Biol. Chem. 276 (16): 12974–82. doi:10.1074/jbc.M008089200. PMID 11150294.
  7. Ullmer C, Schmuck K, Figge A, Lübbert H (March 1998). "Cloning and characterization of MUPP1, a novel PDZ domain protein". FEBS Lett. 424 (1–2): 63–8. doi:10.1016/s0014-5793(98)00141-0. PMID 9537516. S2CID 25328791.
  8. Mancini A, Koch A, Stefan M, Niemann H, Tamura T (September 2000). "The direct association of the multiple PDZ domain containing proteins (MUPP-1) with the human c-Kit C-terminus is regulated by tyrosine kinase activity". FEBS Lett. 482 (1–2): 54–8. doi:10.1016/s0014-5793(00)02036-6. PMID 11018522. S2CID 40159587.
  9. Kimber WA, Trinkle-Mulcahy L, Cheung PC, Deak M, Marsden LJ, Kieloch A, Watt S, Javier RT, Gray A, Downes CP, Lucocq JM, Alessi DR (February 2002). "Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo". Biochem. J. 361 (Pt 3): 525–36. doi:10.1042/0264-6021:3610525. PMC 1222335. PMID 11802782.

Further reading


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