MRM1 (gene)

MRM1
Identifiers
Aliases	MRM1, mitochondrial rRNA methyltransferase 1
External IDs	OMIM: 618099 MGI: 2443470 HomoloGene: 40307 GeneCards: MRM1
Gene location (Human)
Chr.	Chromosome 17 (human)[1]
End	36,608,964 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	84,710,341 bp[2]
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; left ventricle; ; right adrenal gland; ; left adrenal gland; ; right lobe of liver; ; spleen; ; skeletal muscle tissue; ; lymph node; ; duodenum; ; body of pancreas;
	Top expressed in
	interventricular septum; ; extraocular muscle; ; yolk sac; ; right ventricle; ; myocardium of ventricle; ; cumulus cell; ; aortic valve; ; soleus muscle; ; digastric muscle; ; blood;
	More reference expression data
	n/a
Gene ontology
Molecular function	methyltransferase activity; RNA methyltransferase activity; transferase activity; protein binding; rRNA (guanosine-2'-O-)-methyltransferase activity; RNA binding;
Cellular component	mitochondrion; mitochondrial matrix;
Biological process	rRNA processing; methylation; RNA processing; enzyme-directed rRNA 2'-O-methylation; rRNA 2'-O-methylation;
	Sources:Amigo / QuickGO
Orthologs
	79922
	217038
	ENSG00000274853; ENSG00000278619
	ENSMUSG00000018405
	Q6IN84
	Q99J25
	NM_024864
	NM_145433
	NP_079140
	NP_663408
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial rRNA methyltransferase 1 is a protein that in humans is encoded by the MRM1 gene. [5]

References

Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (September 2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLOS ONE. 5 (9): e12862. Bibcode:2010PLoSO...512862H. doi:10.1371/journal.pone.0012862. PMC 2943476. PMID 20877624.

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