MXRA8

MXRA8
Identifiers
Aliases	MXRA8, matrix remodeling associated 8, ASP3
External IDs	OMIM: 617293 MGI: 1922011 HomoloGene: 11500 GeneCards: MXRA8
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	1,361,777 bp[1]
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)[2]
End	155,928,545 bp[2]
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; tibial nerve; ; canal of the cervix; ; right coronary artery; ; gallbladder; ; ascending aorta; ; gastric mucosa; ; left coronary artery; ; left uterine tube; ; right lobe of thyroid gland;
	Top expressed in
	calvaria; ; right lung; ; ankle; ; body of femur; ; left lung; ; right lung lobe; ; molar; ; trachea; ; belly cord; ; sciatic nerve;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function;
Cellular component	integral component of membrane; cell surface; extracellular exosome; membrane; endoplasmic reticulum lumen; nucleus; cytoplasm; plasma membrane; bicellular tight junction; cell junction; cell projection; ciliary membrane;
Biological process	establishment of glial blood-brain barrier; post-translational protein modification; viral process; cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	54587
	74761
	ENSG00000162576
	ENSMUSG00000029070
	Q9BRK3
	Q9DBV4
	NM_032348; NM_001282582; NM_001282583; NM_001282584; NM_001282585
	NM_024263
	NP_001269511; NP_001269512; NP_001269513; NP_001269514; NP_115724
	NP_077225
	Wikidata
View/Edit Human	View/Edit Mouse

Matrix remodeling associated 8 is a protein that in humans is encoded by the MXRA8 gene.[5]

MXRA8 protein is a receptor for multiple arthritogenic alphaviruses, including chikungunya, Ross River, Mayaro and O'nyong nyong viruses.[6]

References

GRCh38: Ensembl release 89: ENSG00000162576 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000029070 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Matrix remodeling associated 8". Retrieved 2018-10-22.
Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, et al. (May 2018). "Mxra8 is a receptor for multiple arthritogenic alphaviruses". Nature. 557 (7706): 570–574. doi:10.1038/s41586-018-0121-3. PMC 5970976. PMID 29769725.

Yonezawa T, Ohtsuka A, Yoshitaka T, Hirano S, Nomoto H, Yamamoto K, Ninomiya Y (December 2003). "Limitrin, a novel immunoglobulin superfamily protein localized to glia limitans formed by astrocyte endfeet". Glia. 44 (3): 190–204. doi:10.1002/glia.10279. PMID 14603461. S2CID 42175289.
Warnatz HJ, Schmidt D, Manke T, Piccini I, Sultan M, Borodina T, et al. (July 2011). "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle". The Journal of Biological Chemistry. 286 (26): 23521–23532. doi:10.1074/jbc.M111.220178. PMC 3123115. PMID 21555518.

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