Manu Platt

Manu Omar Platt (born 1980) is an American biomedical engineer who is a professor at the Georgia Institute of Technology Wallace H. Coulter Department of Biomedical Engineering. He serves as Diversity Director of the Center on Emergent Behaviors of Integrated Cellular Systems.

Manu Omar Platt
Born1979 (age 43–44)
Alma materMorehouse College
Georgia Institute of Technology
Scientific career
InstitutionsMassachusetts Institute of Technology
Georgia Institute of Technology
ThesisRole of shear stress in the differential regulation of endothelial cathepsins and cystatin C (2006)

Early life and education

Platt is the son of a veteran of the United States Air Force.[1] He spent his high school years in Dover, Delaware. As a high school student, Platt took part in science enrichment programmes at Delaware State University.[1] He earned his undergraduate degree at Morehouse College, where he studied biology as an ARCS Foundation scholar.[2][3] At Morehouse, Platt was mentored by Robert M. Nerem, and he took part in the Morehouse SPACE scholar programme.[1][4] On Nerem's advice Platt moved to the Georgia Institute of Technology for his graduate studies, where he worked with Hanjoong Jo on endothelial cell biology. His doctoral research was performed in collaboration with Emory University School of Medicine, as one of the first students to be part of the newly established biomedical engineering program. After earning his doctoral degree he joined Massachusetts Institute of Technology (MIT).

Research and career

In 2009 Platt was appointed to the faculty of the Coulter Department of Biomedical Engineering at Georgia Tech, where he investigates the proteolytic mechanisms of disease, with a focus on conditions that impact Black communities.[5][6] He has concentrated on reducing the occurrence of stroke in patients with sickle cell disease.[6]

Platt has investigated how scientific discoveries have impacted the governmental response to HIV/AIDS.[7] He studied the various bills introduced by the United States Congress, and found that whilst the number of bills was related to breakthroughs in scientific research, it did not impact the passage of laws.[7]

Platt is the founding director of Engaging New Generations at Georgia Tech through Engineering and Science (ENGAGES), a biotechnology and engineering research scheme for African American high school students.[8][9] He delivered the 2017 Biomedical Engineering Society lecture, where he spoke about being from an underrepresented group in science, “Often, if you are the first or the only of a particular demographic category, the path is neither well paved, nor well lit,”.[10] He remarked that scientists can feel like they are waiting for the “perfect time,” to be impactful in promoting diversity and inclusion.[10] In 2019 he was selected as a Keystone Symposia Fellow.[11] In response to the George Floyd protests, universities released statements that called out racism within their research institutions. Platt wrote a perspective piece for Nature Reviews Materials on racism within academia, in which he wrote, “It is said that science is a meritocracy; however, that only holds true if Black professors’ existence is accepted,”.[12]

Presentations

"Danger of Waiting for 'Perfect Time' to Promote Diversity and Inclusion." Lecture presented to the University of Arkansas, Biomedical Engineering Seminar, September 13, 2018.

Awards and honours
  • NIH/International AIDS Society Scholarship[5]
  • National Institutes of Health Director's New Innovator Award[13]
  • Georgia Tech Biomedical Engineering Society Diversity Award[14]
  • Georgia Distinguished Cancer Scientist Award[15]
  • Emerging Scholar, Diverse: Issues in Higher Education magazine[16]

Selected publications
  • Barabino, Gilda A.; Platt, Manu O.; Kaul, Dhananjay K. (2010-08-15). "Sickle Cell Biomechanics". Annual Review of Biomedical Engineering. 12 (1): 345–367. doi:10.1146/annurev-bioeng-070909-105339. ISSN 1523-9829. PMID 20455701.
  • Sorescu, George P.; Sykes, Michelle; Weiss, Daiana; Platt, Manu O.; Saha, Aniket; Hwang, Jinah; Boyd, Nolan; Boo, Yong C.; Vega, J. David; Taylor, W. Robert; Jo, Hanjoong (2003-08-15). "Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Stimulates an Inflammatory Response". Journal of Biological Chemistry. 278 (33): 31128–31135. doi:10.1074/jbc.M300703200. ISSN 0021-9258. PMID 12766166. S2CID 37233984.
  • Sorescu George P.; Song Hannah; Tressel Sarah L.; Hwang Jinah; Dikalov Sergey; Smith Debra A.; Boyd Nolan L.; Platt Manu O.; Lassègue Bernard; Griendling Kathy K.; Jo Hanjoong (2004-10-15). "Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Induces Monocyte Adhesion by Stimulating Reactive Oxygen Species Production From a Nox1-Based NADPH Oxidase". Circulation Research. 95 (8): 773–779. doi:10.1161/01.RES.0000145728.22878.45. PMID 15388638. S2CID 1016941.

Personal life

Platt is one of six sons, including political science researcher Matthew B. Platt.[7][17] He is a master of origami.[11]

References
  1. "Platt a Groundbreaker in Emerging Field". Diverse. 2015-02-02. Retrieved 2020-09-28.
  2. "Manu O. Platt, Ph.D." ASM.org. Retrieved 2020-09-28.
  3. "Morehouse Luncheon and Scholar Presentations | Atlanta". atlanta.arcsfoundation.org. Retrieved 2020-09-28.
  4. "S.P.A.C.E. Program | Morehouse College". www.morehouse.edu. Retrieved 2020-09-28.
  5. "NIH Director's New Innovator Award Program - 2010 Award Recipients | NIH Common Fund". commonfund.nih.gov. 18 September 2018. Retrieved 2020-09-28.
  6. Pollock, Anne; Roy, Deboleena; Platt, Manu O.; Adams, Morgann; Dusabamoro, Theophilia; Fearce, Chelesa; Fennell, Imani; Gaillard, Ebony; Harrison, Courtney; Sihwa, Daphney; Williams, Phoenix (2017-10-18). "How do Black Lives Matter in Teaching, Lab Practices, and Research?". Catalyst: Feminism, Theory, Technoscience. 3 (1): 1–38. doi:10.28968/cftt.v3i1.28793. ISSN 2380-3312.
  7. "Two Brothers, One Paper: BME's Manu Platt and Harvard's Matthew Platt Publish AIDS Paper | Coulter Department of Biomedical Engineering at Georgia Tech and Emory University". bme.gatech.edu. Retrieved 2020-09-28.
  8. "Dr. Manu Platt". www.gtsaa.com. Retrieved 2020-09-28.
  9. "Project ENGAGES: Students get science, math & tech training". Atlanta INtown Paper. 2015-01-05. Retrieved 2020-09-28.
  10. "Revisiting Manu Platt's 2017 Biomedical Engineering Society Diversity Lecture | Coulter Department of Biomedical Engineering at Georgia Tech and Emory University". bme.gatech.edu. Retrieved 2020-09-28.
  11. "Keystone Symposia Fellow Manu Platt on Mentorship and Career Advancement". KeyPoint. Keystone Symposia. 2019-09-18. Retrieved 2020-09-28.
  12. Platt, Manu O. (2020-09-24). "We exist. We are your peers". Nature Reviews Materials. 5 (11): 783–784. Bibcode:2020NatRM...5..783P. doi:10.1038/s41578-020-00248-x. ISSN 2058-8437. S2CID 221884242.
  13. "Manu Platt Wins $1.5M NIH Director's New Innovator Award | Coulter Department of Biomedical Engineering at Georgia Tech and Emory University". bme.gatech.edu. Retrieved 2020-09-28.
  14. "Manu Platt Receives Diversity Award | Coulter Department of Biomedical Engineering at Georgia Tech and Emory University". bme.gatech.edu. Retrieved 2020-09-28.
  15. "Cancer Research Awardees Named; GCC Scholar Achievements". archive.constantcontact.com. Retrieved 2020-09-28.
  16. "BME's Manu Platt featured in Diverse Issues in Higher Education Magazine". Georgia Tech College of Engineering. Retrieved 2020-09-28.
  17. Morehouse College. "Morehouse College | MPlattbio". www.morehouse.edu. Retrieved 2020-09-28.
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