María Domínguez Castellano

María Domínguez Castellano (born 1965, Alcántara, Spain)[1] is a Spanish neuroscientist and director of the Department of Developmental Neurobiology in the Institute of Neurosciences, Alicante, Spain, which is a joint Miguel Hernández University of Elche (UMH) and Spanish National Research Council (CSIC) institution.[2][3][4]

Biography

She has a B.S. in biochemistry from the University of Seville and a Ph.D. in developmental biology from the Autonomous University of Madrid.[2] Her doctoral thesis title was "Función del gen asense del complejo génico achaete-scute en la generación de los órganos sensoriales de Drosophila melanogaster" ("Role of the asense gene of the achaete-scute gene complex in the generation of the sensory organs of Drosophila melanogaster ").[5] She worked at University of Zurich and the University of Cambridge before taking up a post at the Institute of Neurosciences (UMH-CSIC) in 2000. She became a full professor in 2008, and Director of the Department of Developmental Neurobiology in 2016.[2]

In 2008 she won the Alberto Sols prize, with the jury citing "the study of the development and formation of the retina as a neural model, a study that in turn has revealed new mechanisms of cancer development"[6] and the Francisco Cobos prize for Biomedical Research.[7]

Since 2007, she has been a member of the European Molecular Biology Organization (EMBO).[8] She is a member of Asociación de Mujeres Investigadoras y Tecnólogas (AMIT), the Association of Women Researchers and Technologists.[3]

Selected publications
  • Gutierrez-Perez, I., Jordan-Rowley, J., Lyu, X., Valadez-Graham, V., Vallejo, D.M., Ballesta-Illan, E., Lopez-Atalaya, J.P., Kremsky, I., Caparros, E., Corce, V.G., Dominguez, M " Ecdysone-Induced 3D Chromatin Reorganization Involves Active Enhancers Bound by Pipsqueak and Polycomb. " Cell Rep . 28(10), 2715 - 2727.e5 (2019)
  • Reiff, T., Antonello, Z.A., Ballesta-Illán, E., Mira, L., Sala, S., Navarro, M., Martinez, L.M., Dominguez, M " Notch and EGFR regulate apoptosis in progenitor cells to ensure gut homeostasis in Drosophila. " EMBO J . 4, 38(21) - e101346 (2019)
  • Villegas, S.N, Gombos, R., García-López, L., Gutiérrez-Pérez, I., García-Castillo, J., Vallejo, D.M., Da Ros, V., Ballesta-Illán, E., Mihály, J., Dominguez, M. " PI3K/Akt Cooperates with Oncogenic Notch by Inducing Nitric Oxide-Dependent Inflammation. " Cell Rep . 22(10), 2541 - 2549 (2018)
  • Vallejo DM., Juarez-Carreño S., Bolivar J., Morante J., Dominguez M. " A brain circuit that synchronizes growth and maturation revealed through Dilp8 binding to Lgr3. " Science . 350(6262), - aac6767 (2015)
  • Garelli, A, Gontijo, A,, Miguela, V,, Caparros, E,, Dominguez, M " Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation time. " Science . 336(6081), 579 - 582 (2012)

References
  1. Alvarez Amaro, Javier (27 January 2006). "María Domínguez Castellano Investigadora del CSIC : "Alcántara ha cambiado mucho, pero me encanta"". El Periódico Extremadura. Archived from the original on 23 May 2010. Retrieved 3 May 2021.
  2. "People: María Dominguez Castellano". in.umh-csic.es. Instituto de Neurociencias de Alicante. Retrieved 3 May 2021.
  3. "María Domínguez Castellano". AMIT (in Spanish). Asociación de Mujeres Investigadoras y Tecnólogas. 20 July 2016. Retrieved 3 May 2021.
  4. "Extremeños Ilustres: MARÍA DOMÍNGUEZ CASTELLANO". Extremeños Ilustres. 11 January 2019. Retrieved 3 May 2021.
  5. "María Domínguez Castellano". Dialnet (in Spanish). Retrieved 3 May 2021.
  6. "Premio Francisco Cobos · Archivo Histórico: 2008". Fundación Francisco Cobos (in Spanish). Retrieved 3 May 2021.
  7. "La investigadora María Domínguez recibe el IX Premio Francisco Cobos a la investigación Biomédica". Agencia SINC (in Mexican Spanish). Retrieved 2021-05-28.
  8. "Find people in the EMBO Communities". people.embo.org. Retrieved 2021-05-28.
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