Mechanical index

Mechanical index (MI) is a unitless ultrasound metric. It is defined as [1]

where

  • Pr is the peak rarefaction pressure of the ultrasound wave (MPa), derated by an attenuation factor to account for in-tissue acoustic attenuation
  • fc is the center frequency of the ultrasound pulse (MHz).

MI is measured with a calibrated hydrophone in a tank of degassed water. The pulse pressure amplitudes are measured along the central axis of the ultrasound beam. The Pr is calculated by reducing it using an attenuation coefficient of 0.3 dB/cm/MHz.[2]

MI is a unitless number that can be used as an index of cavitation bio-effects; a higher MI value indicates greater exposure. Levels below 0.3 are generally considered to have no detectable effects. Currently the FDA stipulates that diagnostic ultrasound scanners cannot exceed a mechanical index of 1.9.[3]

References
  1. Thomas Szabo (2004). Diagnostic Ultrasound Imaging: Inside Out (Biomedical Engineering). ISBN 978-0-12-680145-3
  2. Postema M (2011). Fundamentals of Medical Ultrasonics. London: CRC Press. doi:10.1201/9781482266641. ISBN 978-0-203-86350-3.
  3. http://www.accessdata.fda.gov/cdrh_docs/pdf9/K091970.pdf (accessed July 2010)


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