Meltzer's triad
Meltzer's triad describes the classical symptoms suggesting the diagnosis of cryoglobulinaemia of polyclonal CGs seen in essential-, viral-, or connective tissue disease-associated cryoglobulinaemia.[1] Meltzer's triad was first described in 1966 by Meltzer and Franklin in cases of essential mixed cryoglobulinemia. This triad is generally seen with types II and III cryoglobulinemia and is seen in up to 25-30% of patients.[2]
| Meltzer's triad | |
|---|---|
| Differential diagnosis | cryoglobulinaemia |
The triad consists of:
- palpable purpura
- arthralgia (joint pain)
- weakness.
References
- "Cryoglobulinaemia. Free medical information. Patient". patient.info.
- "Cryoglobulinemia Clinical Presentation: History, Physical Examination". emedicine.medscape.com. Retrieved 2023-09-20.
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