Michael Roden

Michael Roden (born February 11, 1961) is Professor and Chairman of Internal Medicine, Endocrinology and Metabolic Disorders at Heinrich Heine University Düsseldorf, Director of the Division of Endocrinology and Diabetology at the University Hospital of Düsseldorf and Spokesman for the Executive Board and Scientific Director of the German Diabetes Center, the Leibniz Center for Diabetes Research at the Heinrich Heine University Düsseldorf (Legal body: Deutsche Diabetes-Forschungsgesellschaft eV).

Michael Roden
Michael Roden

Career and appointments

After finishing high school at Akademisches Gymnasium Vienna, Austria, and study of medicine in 1986 at the University of Vienna, he started his career as an assistant at the Pharmacological Institute.  In 1988, he began working at the 1st Medical University Clinic of the University of Vienna, where he acquired the “venia legendi” in Internal Medicine in 1994. He then worked as Max-Kade Fellow in the Section of Endocrinology at Yale University in 1994/1995. After returning to the Division for Endocrinology and Metabolism at the University Clinic of Internal Medicine III at the General Hospital Vienna as a senior physician, he was appointed as Associate Professor in 1997. From 2003 to 2009, he served as chairman and director of the 1st Medical Department including the Division of Nephrology at Hanusch Hospital, Teaching Hospital of the Medical University of Vienna. In 2005, he founded the Karl Landsteiner Institute for Endocrinology and Metabolic Diseases. After accepting the call as chairman and professor in Düsseldorf, he became a board member of the German Center for Diabetes Research in 2009. In 2016, he was appointed by the Federal President of Germany as a member of the Science Council of the Federal Government and the Governments of the federal states of Germany. Since 2017, he has been contributing his knowledge and experience there as Chairman of its Medical Committee.[1] As President, he led the 54th annual meeting of the German Diabetes Association in 2019 with the slogan "Diabetes - Not only a question of type".[2] In addition, Roden is a member of numerous scientific advisory boards such as the Scientific Advisory Board of the Medical University of Vienna.

Research contributions

Michael Roden’s research focusses on energy metabolism in humans under physiological conditions and with metabolic disorders such as metabolic syndrome, diabetes mellitus and non-alcoholic fatty liver disease.[3][4] He has made major contributions to our understanding of the cellular mechanisms of fatty acid-[5][6][7][8] and amino acid-induced insulin resistance in humans.[9] Additionally, he examined the function of mitochondria in muscle and liver tissue. With his research group, he is contributing to the development of novel non-invasive methods for real-time analysis of tissue-specific metabolism.[10][11] His studies demonstrated that alterations of mitochondrial function can decisively influence the development and progress of diabetes and non-alcoholic fatty liver disease.[12][13] His recent research contributes to a novel differentiation of diabetes subtypes with various risks for their sequelae and promotes the way to precision medicine for people with diabetes.[14]

Roden is the author of more than 700 "peer-reviewed" publications, co-author of (inter)national guidelines[15][16] and the editor of the book "Clinical Diabetes Research: Methods and Techniques".[17] According to the Scopus database, it has an h-index of 103.

Selected honors & awards
  • 2001: Ferdinand-Bertram Award of the German Diabetes Society
  • 2001: Novartis (Sandoz) Award for Chemistry, Biology, Medicine, Austria
  • 2004: International Novartis Award for Innovative Patient Oriented Research
  • 2006: ESCI (Mack-Foster) Award for Excellence in Clinical Sciences
  • 2006: Oskar-Minkowski Award of the European Association for the Study of Diabetes
  • 2013: Honorary doctorate from the Medical Faculty of the University of Belgrade
  • 2014: Somogyi Award of the Hungarian Diabetes Society (Magyar Diabetes Társaság)
  • 2016: Honorary doctorate from the Medical Faculty of the National and Kapodistrian University Athens
  • 2017: Paul-Langerhans Medal of the German Diabetes Society (DDG)[18]
  • 2018: G. B. Morgagni Prize and Gold Medal Career Achievement[19]
  • 2021: Werner-Creutzfeldt-Prize of the German Diabetes Society[20]
  • 2021: Honorary membership of the Hungarian Diabetes Society[21]
  • 2022: Membership of the National Academy of Sciences Leopoldina, section Internal Medicine and Dermatology[22]
  • 2022: Membership of the Academia Europaea[23]
  • 2022: Highly Cited Researcher according to Clarivate Analytics[24]

References
  1. "Wissenschaftsrat - Medizin". www.wissenschaftsrat.de. Retrieved 2020-02-04.
  2. "Deutsche Diabetes Gesellschaft: Deutsche Diabetes Gesellschaft mit 54. Diabetes Kongress in Berlin: Diabetesklassifikation, Remission und genderbezogene Aspekte". www.deutsche-diabetes-gesellschaft.de. Retrieved 2020-02-04.
  3. Gancheva, Sofiya; Jelenik, Tomas; Álvarez-Hernández, Elisa; Roden, Michael (2018). "Interorgan metabolic crosstalk in human insulin resistance". Physiological Reviews. 98 (3): 1371–1415. doi:10.1152/physrev.00015.2017. ISSN 0031-9333. PMID 29767564.
  4. Hernández, Elisa Álvarez; Kahl, Sabine; Seelig, Anett; Begovatz, Paul; Irmler, Martin; Kupriyanova, Yuliya; Nowotny, Bettina; Nowotny, Peter; Herder, Christian; Barosa, Cristina; Carvalho, Filipa; Rozman, Jan; Neschen, Susanne; Jones, John G.; Beckers, Johannes; de Angelis, Martin Hrabě; Roden, Michael (2017). "Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance". Journal of Clinical Investigation. 127 (2): 695–708. doi:10.1172/JCI89444. ISSN 0021-9738. PMC 5272194. PMID 28112681.
  5. Stefan, Norbert; Roden, Michael (2019). "Diabetes and Fatty Liver". Experimental and Clinical Endocrinology & Diabetes. 127 (S 01): S93–S96. doi:10.1055/a-0984-5753. ISSN 0947-7349. PMID 31860928.
  6. Apostolopoulou, Maria; Gordillo, Ruth; Koliaki, Chrysi; Gancheva, Sofia; Jelenik, Tomas; De Filippo, Elisabetta; Herder, Christian; Markgraf, Daniel; Jankowiak, Frank; Esposito, Irene; Schlensak, Matthias; Scherer, Philipp E.; Roden, Michael (2018). "Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis". Diabetes Care. 41 (6): 1235–1243. doi:10.2337/dc17-1318. ISSN 0149-5992. PMID 29602794.
  7. Szendroedi, Julia; Yoshimura, Toru; Phielix, Esther; Koliaki, Chrysi; Marcucci, Mellissa; Zhang, Dongyan; Jelenik, Tomas; Müller, Janette; Herder, Christian; Nowotny, Peter; Shulman, Gerald I.; Roden, Michael (2014). "Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans". Proceedings of the National Academy of Sciences. 111 (26): 9597–9602. doi:10.1073/pnas.1409229111. ISSN 0027-8424. PMC 4084449. PMID 24979806.
  8. Roden, M.; Krssak, M.; Stingl, H.; Gruber, S.; Hofer, A.; Furnsinn, C.; Moser, E.; Waldhausl, W. (1999). "Rapid impairment of skeletal muscle glucose transport/phosphorylation by free fatty acids in humans". Diabetes. 48 (2): 358–364. doi:10.2337/diabetes.48.2.358. ISSN 0012-1797. PMID 10334314.
  9. Krebs, M.; Krssak, M.; Bernroider, E.; Anderwald, C.; Brehm, A.; Meyerspeer, M.; Nowotny, P.; Roth, E.; Waldhausl, W.; Roden, M. (2002). "Mechanism of Amino Acid-Induced Skeletal Muscle Insulin Resistance in Humans". Diabetes. 51 (3): 599–605. doi:10.2337/diabetes.51.3.599. ISSN 0012-1797. PMID 11872656.
  10. Schmid, A. I.; Szendroedi, J.; Chmelik, M.; Krssak, M.; Moser, E.; Roden, M. (2011). "Liver ATP Synthesis Is Lower and Relates to Insulin Sensitivity in Patients With Type 2 Diabetes". Diabetes Care. 34 (2): 448–453. doi:10.2337/dc10-1076. ISSN 0149-5992. PMC 3024365. PMID 21216854.
  11. Kunert, O.; Stingl, H.; Rosian, E.; Krssak, M.; Bernroider, E.; Seebacher, W.; Zangger, K.; Staehr, P.; Chandramouli, V.; Landau, B.R.; Nowotny, P.; Waldhausl, W.; Haslinger, E.; Roden, M. (2003). "Measurement of Fractional Whole-Body Gluconeogenesis in Humans From Blood Samples Using 2H Nuclear Magnetic Resonance Spectroscopy". Diabetes. 52 (10): 2475–2482. doi:10.2337/diabetes.52.10.2475. ISSN 0012-1797. PMID 14514629.
  12. Gancheva, Sofiya; Ouni, Meriem; Jelenik, Tomas; Koliaki, Chrysi; Szendroedi, Julia; Toledo, Frederico G. S.; Markgraf, Daniel F.; Pesta, Dominik H.; Mastrototaro, Lucia; De Filippo, Elisabetta; Herder, Christian; Jähnert, Markus; Weiss, Jürgen; Strassburger, Klaus; Schlensak, Matthias; Schürmann, Annette; Roden, Michael (2019). "Dynamic changes of muscle insulin sensitivity after metabolic surgery". Nature Communications. 10 (1): 4179. doi:10.1038/s41467-019-12081-0. ISSN 2041-1723. PMC 6744497. PMID 31519890.
  13. Koliaki, Chrysi; Szendroedi, Julia; Kaul, Kirti; Jelenik, Tomas; Nowotny, Peter; Jankowiak, Frank; Herder, Christian; Carstensen, Maren; Krausch, Markus; Knoefel, Wolfram Trudo; Schlensak, Matthias; Roden, Michael (2015). "Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis". Cell Metabolism. 21 (5): 739–746. doi:10.1016/j.cmet.2015.04.004. ISSN 1550-4131. PMID 25955209.
  14. Zaharia, Oana P; Strassburger, Klaus; Strom, Alexander; Bönhof, Gidon J; Karusheva, Yanislava; Antoniou, Sofia; Bódis, Kálmán; Markgraf, Daniel F; Burkart, Volker; Müssig, Karsten; Hwang, Jong-Hee; Asplund, Olof; Groop, Leif; Ahlqvist, Emma; Seissler, Jochen; Nawroth, Peter; Kopf, Stefan; Schmid, Sebastian M; Stumvoll, Michael; Pfeiffer, Andreas F H; Kabisch, Stefan; Tselmin, Sergey; Häring, Hans U; Ziegler, Dan; Kuss, Oliver; Szendroedi, Julia; Roden, Michael (2019). "Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study". The Lancet Diabetes & Endocrinology. 7 (9): 684–694. doi:10.1016/S2213-8587(19)30187-1. ISSN 2213-8587. PMID 31345776.
  15. Harreiter, Jürgen; Roden, Michael (2019). "Diabetes mellitus – Definition, Klassifikation, Diagnose, Screening und Prävention (Update 2019)". Wiener klinische Wochenschrift. 131 (S1): 6–15. doi:10.1007/s00508-019-1450-4. ISSN 0043-5325. PMID 30980151. S2CID 111391123.
  16. European Association for the Study of the Liver (EASL); European Association for the Study of Diabetes (EASD); European Association for the Study of Obesity (EASO) (2016). "EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease". Journal of Hepatology. 64 (6): 1388–1402. doi:10.1016/j.jhep.2015.11.004. ISSN 0168-8278. PMC 5644799. PMID 27062661.
  17. Roden, Michael (2007). Clinical diabetes research : methods and techniques. Chichester, West Sussex, England Hoboken, NJ: John Wiley & Sons. ISBN 9780470017289.
  18. "Deutsche Diabetes Gesellschaft: Träger der Paul-Langerhans-Medaille" (PDF). www.ddg.info. Retrieved 2023-05-23.
  19. "Professor Michael Roden erhält Morgagni Goldmedaille 2018 - Deutsches Diabetes-Zentrum (DDZ)". www.ddz.de. Retrieved 2023-05-23.
  20. "Deutsche Diabetes Gesellschaft: Werner-Creutzfeldt-Preisträger" (PDF). www.ddg.info. Retrieved 2023-05-23.
  21. "Professor Michael Roden zum neuen Ehrenmitglied der Ungarischen Diabetes Gesellschaft ernannt". www.ddz.de. Retrieved 2023-05-23.
  22. "Mitgliedseintrag von Michael Roden bei der Nationalen Akademie der Wissenschaften Leopoldina". www.leopoldina.org. Retrieved 2023-05-23.
  23. "Mitgliedseintrag von Michael Roden bei der Akademia Europaea". www.ae-info.org. Retrieved 2023-05-23.
  24. "Michael Roden - Highly Cited Researcher in the field of Cross-Field - 2022". www.webofscience.com. Retrieved 2023-05-23.
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