Missouri Route 32

Route 32 leaves Interstate 44 Business and joins Route 5/Route 64 in Lebanon.

The highway begins at the beginning of state maintenance, at a point in the 300 block of 4th Street in Ste. Genevieve. City streets connect to a ferry providing passage across the Mississippi River to Illinois. Just before leaving the city, the route comes to an intersection with U.S. Route 61. Six miles further west is an interchange with Interstate 55 and eleven miles (18 km) west of the interstate is the northern junction of Route 144. At Farmington, the highway joins U.S. Route 67 for seven miles (6 km), then it exits at Leadington and turns into four lane to Saint Joe State Park U.S. Route 67 Business.

At Caledonia, the highway turns south and forms a four-mile (6 km) concurrency with Route 21, then turns west and enters the Mark Twain National Forest. In the national forest, the highway forms a six-mile (10 km) concurrency with Route 49. As the highway nears the western boundary of the Mark Twain National Forest, the highway joins Route 72, the two highways will be united to the west side of Salem. Nine miles west of Salem is the northern terminus of Route 119.

At Licking is the northern terminus of Route 137 and an intersection with U.S. Route 63. West of Licking, Route 32 enters another section of the Mark Twain National Forest. At Success, Route 32 turns north, joining Route 17 for four miles (6 km) then turns west again at Roby. At Lynchburg is the northern terminus of Route 95 and Route 32 turns north. Three miles northwest of Falcon, the highway leaves the Mark Twain National Forest.

At Lebanon, Route 32 joins Route 5 and has an interchange with Interstate 44, which also serves as the eastern terminus of Route 64. In Lebanon, the highway turns southwest and leaves the concurrency with Route 5 and Route 64.

At Buffalo, Route 32 forms a brief concurrency with Route 73, which it joins to the terminus of Route 73 at U.S. Route 65. The road then continues west, forming the main highway between the two county seats of Buffalo and Bolivar. At Bolivar, the highway intersect Route 83, and then intersects Route 13.

At Fair Play, Route 32 briefly joins Route 123 and begins a northwest route to the north side of Stockton Lake where the highway passes over the dam. At Stockton, it joins Route 39 briefly and continue west eventually reaching the northern terminus of Route 97. At this intersection, the highway turns due north for five miles (8 km) before reaching U.S. Route 54 and ending in eastern El Dorado Springs.

The section of Route 32 between Route 17 and Plato was formerly designated as Route 17A.