Morogoro virus

Morogoro virus
Virus classification
(unranked):	Virus
Realm:	Riboviria
Kingdom:	Orthornavirae
Phylum:	Negarnaviricota
Class:	Ellioviricetes
Order:	Bunyavirales
Family:	Arenaviridae
Genus:	Mammarenavirus
Virus:	Morogoro virus

Morogoro virus is an East African arenavirus infecting the multimammate mouse (Mastomys natalensis).[1] The virus is genetically closely related to Lassa virus, known to cause Lassa fever in humans. Morogoro virus, however, does not seem to infect humans.[1] Transmission of Morogoro virus between mice is assumed to occur via direct and indirect contact.[2] Infected animals pass a latent period of 7 days and subsequently shed the virus for about 30 days, after which they recover and develop lifelong antibodies.[3] Transmission may also be possible from infected mothers to offspring and through sexual contact, as this has been suggested for other arenaviruses.[4][5]

References

Günther S, Hoofd G, Charrel R, Röser C, Becker-Ziaja B, Lloyd G, Sabuni C, Verhagen R, van der Groen G, Kennis J, Katakweba A, Machang'u R, Makundi R, Leirs H (December 2009). "Mopeia virus-related arenavirus in natal multimammate mice, Morogoro, Tanzania". Emerg Infect Dis. 15 (12): 2008–2012. doi:10.3201/eid1512.090864. PMC 3044542. PMID 19961688.
Borremans B, Leirs H, Gryseels S, Günther S, Makundi R, de Bellocq JG (August 2011). "Presence of Mopeia virus, an African arenavirus, related to biotope and individual rodent host characteristics: implications for virus transmission". Vector Borne Zootic Dis. 11 (8): 1125–1131. doi:10.1089/vbz.2010.0010. PMID 21142956.
Borremans B, Vossen R, Becker-Ziaja B, Gryseels S, Hughes N, Van Gestel M, Van Houtte N, Günther S, Leirs H (29 May 2015). "Shedding dynamics of Morogoro virus, an African arenavirus closely related to Lassa virus, in its natural reservoir host Mastomys natalensis". Sci Rep. 5: 10445. doi:10.1038/srep10445. PMC 4448520. PMID 26022445.
Fichet-Calvet E, Becker-Ziaja B, Koivogui L, Günther S (September 2014). "Lassa serology in natural populations of rodents and horizontal transmission". Vector Borne Zoonotic Dis. 14 (9): 665–674. doi:10.1089/vbz.2013.1484. PMC 4170823. PMID 25229705.
Webb PA, Justines G, Johnson KM (1975). "Infection of wild and laboratory animals with Machupo and Latino viruses". Bull World Health Organ. 52 (4–6): 493–499. PMC 2366657. PMID 182399.

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[gunther-1] Günther S, Hoofd G, Charrel R, Röser C, Becker-Ziaja B, Lloyd G, Sabuni C, Verhagen R, van der Groen G, Kennis J, Katakweba A, Machang'u R, Makundi R, Leirs H (December 2009). "Mopeia virus-related arenavirus in natal multimammate mice, Morogoro, Tanzania". Emerg Infect Dis. 15 (12): 2008–2012. doi:10.3201/eid1512.090864. PMC 3044542. PMID 19961688.

[2] Borremans B, Leirs H, Gryseels S, Günther S, Makundi R, de Bellocq JG (August 2011). "Presence of Mopeia virus, an African arenavirus, related to biotope and individual rodent host characteristics: implications for virus transmission". Vector Borne Zootic Dis. 11 (8): 1125–1131. doi:10.1089/vbz.2010.0010. PMID 21142956.

[3] Borremans B, Vossen R, Becker-Ziaja B, Gryseels S, Hughes N, Van Gestel M, Van Houtte N, Günther S, Leirs H (29 May 2015). "Shedding dynamics of Morogoro virus, an African arenavirus closely related to Lassa virus, in its natural reservoir host Mastomys natalensis". Sci Rep. 5: 10445. doi:10.1038/srep10445. PMC 4448520. PMID 26022445.

[4] Fichet-Calvet E, Becker-Ziaja B, Koivogui L, Günther S (September 2014). "Lassa serology in natural populations of rodents and horizontal transmission". Vector Borne Zoonotic Dis. 14 (9): 665–674. doi:10.1089/vbz.2013.1484. PMC 4170823. PMID 25229705.

[5] Webb PA, Justines G, Johnson KM (1975). "Infection of wild and laboratory animals with Machupo and Latino viruses". Bull World Health Organ. 52 (4–6): 493–499. PMC 2366657. PMID 182399.