NAV1

Neuron navigator 1 is a protein that in humans is encoded by the NAV1 gene.[5][6][7]

NAV1
Identifiers
AliasesNAV1, POMFIL3, STEERIN1, UNC53H1, neuron navigator 1
External IDsOMIM: 611628 MGI: 2183683 HomoloGene: 10719 GeneCards: NAV1
Orthologs
SpeciesHumanMouse
Entrez

89796

215690

Ensembl

ENSG00000134369

ENSMUSG00000009418

UniProt

Q8NEY1

Q8CH77

RefSeq (mRNA)

NM_001167738
NM_020443

NM_173437

RefSeq (protein)

NP_001161210
NP_065176

NP_775613

Location (UCSC)Chr 1: 201.62 – 201.83 MbChr 1: 135.36 – 135.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000134369 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000009418 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Maes T, Barcelo A, Buesa C (Jun 2002). "Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans". Genomics. 80 (1): 21–30. doi:10.1006/geno.2002.6799. PMID 12079279.
  6. Coy JF, Wiemann S, Bechmann I, Bachner D, Nitsch R, Kretz O, Christiansen H, Poustka A (Jun 2002). "Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms". Gene. 290 (1–2): 73–94. doi:10.1016/S0378-1119(02)00567-X. PMID 12062803.
  7. "Entrez Gene: NAV1 neuron navigator 1".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.