NELL2

Protein kinase C-binding protein NELL2 is an enzyme that in humans is encoded by the NELL2 gene.[5]

NELL2
Identifiers
AliasesNELL2, NRP2, neural EGFL like 2
External IDsOMIM: 602320 MGI: 1858510 HomoloGene: 4488 GeneCards: NELL2
Orthologs
SpeciesHumanMouse
Entrez

4753

54003

Ensembl

ENSG00000184613

ENSMUSG00000022454

UniProt

Q99435

Q61220

RefSeq (mRNA)

NM_001145107
NM_001145108
NM_001145109
NM_001145110
NM_006159

NM_001289653
NM_016743
NM_001356950
NM_001356951

RefSeq (protein)

NP_001138579
NP_001138580
NP_001138581
NP_001138582
NP_006150

NP_001276582
NP_001343879
NP_001343880

Location (UCSC)Chr 12: 44.51 – 44.92 MbChr 15: 94.97 – 95.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF) -like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. An alternative splice variant has been described but its full length sequence has not been determined.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000184613 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022454 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: NELL2 NEL-like 2 (chicken)".

Further reading


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