NLGN2

Neuroligin-2 is a protein that in humans is encoded by the NLGN2 gene.[5][6][7]

NLGN2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNLGN2, neuroligin 2
External IDsOMIM: 606479 MGI: 2681835 HomoloGene: 69317 GeneCards: NLGN2
Orthologs
SpeciesHumanMouse
Entrez

57555

216856

Ensembl

ENSG00000169992
ENSG00000283859

ENSMUSG00000051790

UniProt

Q8NFZ4

Q69ZK9

RefSeq (mRNA)

NM_020795

NM_198862
NM_001364137

RefSeq (protein)

NP_065846

NP_942562
NP_001351066

Location (UCSC)Chr 17: 7.4 – 7.42 MbChr 11: 69.71 – 69.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.[7]

References

  1. ENSG00000283859 GRCh38: Ensembl release 89: ENSG00000169992, ENSG00000283859 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000051790 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Philibert RA, Winfield SL, Sandhu HK, Martin BM, Ginns EI (May 2000). "The structure and expression of the human neuroligin-3 gene". Gene. 246 (1–2): 303–10. doi:10.1016/S0378-1119(00)00049-4. PMID 10767552.
  6. Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.
  7. "Entrez Gene: NLGN2 neuroligin 2".

Further reading


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