NOL5A

Nucleolar protein 56 is a protein that in humans is encoded by the NOP56 gene.[5][6]

NOP56
Identifiers
AliasesNOP56, NOL5A, SCA36, NOP56 ribonucleoprotein
External IDsOMIM: 614154 MGI: 1914384 HomoloGene: 4660 GeneCards: NOP56
Orthologs
SpeciesHumanMouse
Entrez

10528

67134

Ensembl

ENSG00000101361

ENSMUSG00000027405

UniProt

O00567

Q9D6Z1

RefSeq (mRNA)

NM_006392

NM_024193

RefSeq (protein)

NP_006383

NP_077155

Location (UCSC)Chr 20: 2.65 – 2.66 MbChr 2: 130.12 – 130.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them have not been determined.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000101361 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027405 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Gautier T, Berges T, Tollervey D, Hurt E (Dec 1997). "Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis". Mol Cell Biol. 17 (12): 7088–98. doi:10.1128/MCB.17.12.7088. PMC 232565. PMID 9372940.
  6. "Entrez Gene: NOL5A nucleolar protein 5A (56kDa with KKE/D repeat)".

Further reading

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