OTUD1
OTU deubiquitinase 1 is a protein that in humans is encoded by the OTUD1 gene. [5]
OTUD1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | OTUD1, DUBA7, OTDC1, OTU deubiquitinase 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 612022 MGI: 1918448 HomoloGene: 45953 GeneCards: OTUD1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.
References
- GRCh38: Ensembl release 89: ENSG00000165312 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000043415 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: OTU deubiquitinase 1". Retrieved 2016-03-13.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human OTU domain-containing protein 1
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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