OTUD4

OTU domain-containing protein 4 is a protein that in humans is encoded by the OTUD4 gene.[5][6][7]

OTUD4
Identifiers
AliasesOTUD4, DUBA6, HIN1, HSHIN1, OTU deubiquitinase 4
External IDsOMIM: 611744 MGI: 1098801 HomoloGene: 35370 GeneCards: OTUD4
Orthologs
SpeciesHumanMouse
Entrez

54726

73945

Ensembl

ENSG00000164164

ENSMUSG00000036990

UniProt

Q01804

B2RRE7

RefSeq (mRNA)

NM_001102653
NM_017493
NM_199324
NM_001366057
NM_001366058

NM_001081164
NM_001256033

RefSeq (protein)

NP_001096123
NP_059963
NP_001352986
NP_001352987

NP_001074633
NP_001242962

Location (UCSC)Chr 4: 145.11 – 145.18 MbChr 8: 80.37 – 80.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. The smaller protein isoform encoded by the shorter transcript variant is found only in HIV-1 infected cells.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000164164 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000036990 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Raineri I, Senn HP (Feb 1993). "HIV-1 promotor insertion revealed by selective detection of chimeric provirus-host gene transcripts". Nucleic Acids Res. 20 (23): 6261–6. doi:10.1093/nar/20.23.6261. PMC 334514. PMID 1475186.
  6. Krop I, Maguire P, Lahti-Domenici J, Lodeiro G, Richardson A, Johannsdottir HK, Nevanlinna H, Borg A, Gelman R, Barkardottir RB, Lindblom A, Polyak K (May 2003). "Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors". Cancer Res. 63 (9): 2024–7. PMID 12727813.
  7. "Entrez Gene: OTUD4 OTU domain containing 4".

Further reading


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