Omphalotus subilludens

Omphalotus subilludens is a fungus species in the genus Omphalotus. The type collection was found by Murrill on July 26, 1944, in Gainesville, Florida. It has also been recorded from Texas.

Bioluminescent Omphalotus subilludens

Omphalotus subilludens
Scientific classification Edit this classification
Domain: Eukaryota
Kingdom: Fungi
Division: Basidiomycota
Class: Agaricomycetes
Order: Agaricales
Family: Omphalotaceae
Genus: Omphalotus
Species:
O. subilludens
Binomial name
Omphalotus subilludens
Synonyms

Clitocybe subilludens (Murrill) Murrill 1945[1]
Monodelphus subilludens Murrill 1945

Atromentin and thelephoric acid are chemical compounds found in cultures of O. subilludens.[2] Atromentin is an effective anticoagulant, and similar in biological activity to the well-known anticoagulant heparin.[3] Atromentin also possesses antibacterial activity, inhibiting the enzyme enoyl-acyl carrier protein reductase (essential for the biosynthesis of fatty acids) in the bacteria Streptococcus pneumoniae.[4]

It also produces illudoids.[5]

References

  1. Murrill, W.A., 1945, Quarterly Journal of the Florida Academy of Science 8(2): 198
  2. Sullivan, G.; Garrett, R. D.; Lenehan, R. F. (1971). "Occurrence of atromentin and thelephoric acid in cultures ofclitocybe subilludens". Journal of Pharmaceutical Sciences. 60 (11): 1727–9. doi:10.1002/jps.2600601134. PMID 4332377.
  3. Khanna JM, Malone MH, Euler KL, Brady LR (1965). "Atromentin – anticoagulant from Hydnellum diabolus". Journal of Pharmaceutical Sciences. 54 (7): 1016–20. doi:10.1002/jps.2600540714. PMID 5862512.
  4. Zheng CJ, Sohn MJ, Kim WG (2006). "Atromentin and leucomelone, the first inhibitors specific to enoyl-ACP reductase (FabK) of Streptococcus pneumoniae". Journal of Antibiotics. 59 (12): 808–12. doi:10.1038/ja.2006.108. PMID 17323650.
  5. Illudoids from Omphalotus olivascens and Clitocybe subilludens. Nair M. S. R., Carey S. T. and Rogerson C. T., Mycologia, 1983, vol. 75, no5, pages 920-922, INIST:9415717


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