OPP
Government
- NASA's Office of Planetary Protection
- One Police Plaza (1PP), the Police headquarters in New York City
- Ontario Provincial Police, the provincial police service of Ontario, Canada
- Opp, Alabama, a city in the United States
- Orleans Parish Prison, prison located in New Orleans, United States
Miscellaneous other organizations
- Omega Psi Phi, an international fraternity
- One People's Project, an anti-racist group
- Opp (newspaper), published in Oppdal, Norway
- Open Prosthetics Project, a project dedicated to creation of public domain prosthetics
- Orangi Pilot Project, a development project in slums of Karachi, Pakistan
Science and technology
- Object Push Profile, a Bluetooth communications protocol based on the OBEX protocol
- Octonionic projective plane, or Cayley plane, a projective plane over the octonions
- Oriented Polypropylene, and specifically BOPP (biaxially oriented PP), a polymer used mainly for packaging and labeling
- Ortho-phenylphenol, or 2-Phenylphenol, an organic compound used as a fungicide
- Ovine progressive pneumonia, or ovine lentivirus, a chronic infection of Visna virus that affects sheep
- Yamaha YM2164, an FM synthesis sound chip also called FM Operator Type P (OPP)
Songs
- "O.P.P." (song), a song by Naughty by Nature from the album Naughty by Nature
- "Opps", a song by Vince Staples and Yugen Blakrok from Black Panther: The Album
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