PDE1B

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene.[5][6][7]

PDE1B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPDE1B, PDE1B1, PDES1B, HEL-S-79p, phosphodiesterase 1B
External IDsOMIM: 171891 MGI: 97523 HomoloGene: 37370 GeneCards: PDE1B
Orthologs
SpeciesHumanMouse
Entrez

5153

18574

Ensembl

ENSG00000123360

ENSMUSG00000022489

UniProt

Q01064

Q01065

RefSeq (mRNA)

NM_001285890
NM_008800
NM_001357980

RefSeq (protein)

NP_001272819
NP_032826
NP_001344909

Location (UCSC)Chr 12: 54.55 – 54.58 MbChr 15: 103.41 – 103.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000123360 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022489 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Jiang X, Li J, Paskind M, Epstein PM (Nov 1996). "Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells". Proc Natl Acad Sci U S A. 93 (20): 11236–41. Bibcode:1996PNAS...9311236J. doi:10.1073/pnas.93.20.11236. PMC 1074519. PMID 8855339.
  6. Yu J, Wolda SL, Frazier AL, Florio VA, Martins TJ, Snyder PB, Harris EA, McCaw KN, Farrell CA, Steiner B, Bentley JK, Beavo JA, Ferguson K, Gelinas R (Feb 1998). "Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1". Cell Signal. 9 (7): 519–29. doi:10.1016/S0898-6568(97)00046-6. PMID 9419816.
  7. "Entrez Gene: PDE1B phosphodiesterase 1B, calmodulin-dependent".

Further reading


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