PHYHIP

PHYHIP
Identifiers
Aliases	PHYHIP, DYRK1AP3, PAHX-AP, PAHXAP1, phytanoyl-CoA 2-hydroxylase interacting protein
External IDs	OMIM: 608511 MGI: 1860417 HomoloGene: 8847 GeneCards: PHYHIP
Gene location (Human)
Chr.	Chromosome 8 (human)[1]
End	22,232,101 bp[1]
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)[2]
End	70,706,272 bp[2]
RNA expression pattern
	Top expressed in
	middle frontal gyrus; ; Brodmann area 10; ; Brodmann area 9; ; nucleus accumbens; ; putamen; ; caudate nucleus; ; frontal pole; ; middle temporal gyrus; ; superior frontal gyrus; ; cerebellar vermis;
	Top expressed in
	superior frontal gyrus; ; cerebellar cortex; ; cerebellar vermis; ; olfactory tubercle; ; piriform cortex; ; prefrontal cortex; ; subiculum; ; primary motor cortex; ; cingulate gyrus; ; lip;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein tyrosine kinase binding;
Cellular component	cytoplasm;
Biological process	xenophagy; positive regulation of defense response to virus by host; protein localization;
	Sources:Amigo / QuickGO
Orthologs
	9796
	105653
	ENSG00000168490
	ENSMUSG00000003469
	Q92561
	Q8K0S0
	NM_001099335; NM_014759; NM_001363311; NM_001363312
	NM_145981
	NP_001092805; NP_055574; NP_001350240; NP_001350241
	NP_666093
	Wikidata
View/Edit Human	View/Edit Mouse

Phytanoyl-CoA 2-hydroxylase interacting protein is a protein that in humans is encoded by the PHYHIP gene. [5]

References

GRCh38: Ensembl release 89: ENSG00000168490 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000003469 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Phytanoyl-CoA 2-hydroxylase interacting protein". Retrieved 2016-07-15.

Bescond M, Rahmani Z (2005). "Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein". Int. J. Biochem. Cell Biol. 37 (4): 775–83. doi:10.1016/j.biocel.2004.12.006. PMID 15694837.

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