PIBF1

Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene.[4][5] It has been shown to localize to the centrosome[6] and has also been named CEP90.[7]

PIBF1
Identifiers
AliasesPIBF1, C13orf24, CEP90, PIBF, progesterone immunomodulatory binding factor 1, JBTS33
External IDsOMIM: 607532 MGI: 1261910 HomoloGene: 4628 GeneCards: PIBF1
Orthologs
SpeciesHumanMouse
Entrez

10464

52023

Ensembl

n/a

ENSMUSG00000022064

UniProt

Q8WXW3

n/a

RefSeq (mRNA)

NM_006346
NM_001349655

NM_029320
NM_029454

RefSeq (protein)

NP_006337
NP_001336584

n/a

Location (UCSC)n/aChr 14: 99.34 – 99.49 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCm38: Ensembl release 89: ENSMUSG00000022064 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Rozenblum E, Vahteristo P, Sandberg T, Bergthorsson JT, Syrjakoski K, Weaver D, Haraldsson K, Johannsdottir HK, Vehmanen P, Nigam S, Golberger N, Robbins C, Pak E, Dutra A, Gillander E, Stephan DA, Bailey-Wilson J, Juo SH, Kainu T, Arason A, Barkardottir RB, Nevanlinna H, Borg A, Kallioniemi OP (Apr 2002). "A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes". Hum Genet. 110 (2): 111–21. doi:10.1007/s00439-001-0646-6. PMID 11935316. S2CID 21371347.
  5. "Entrez Gene: C13orf24 chromosome 13 open reading frame 24".
  6. Lachmann M, Gelbmann D, Kálmán E, et al. (2004). "PIBF (progesterone induced blocking factor) is overexpressed in highly proliferating cells and associated with the centrosome". Int. J. Cancer. 112 (1): 51–60. doi:10.1002/ijc.20326. PMID 15305375.
  7. Kim, K.; Rhee, K. (2011). "The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole". Journal of Cell Science. 124 (Pt 3): 338–347. doi:10.1242/jcs.078329. PMID 21224392.

Further reading


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