Pou class 3 homeobox 3
POU class 3 homeobox 3 is a protein that in humans is encoded by the POU3F3 gene. [5]
Function
This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015].
References
- GRCh38: Ensembl release 89: ENSG00000198914 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000045515 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: POU class 3 homeobox 3". Retrieved 2018-08-13.
Further reading
- Li W, Zheng J, Deng J, You Y, Wu H, Li N, Lu J, Zhou Y (June 2014). "Increased levels of the long intergenic non-protein coding RNA POU3F3 promote DNA methylation in esophageal squamous cell carcinoma cells". Gastroenterology. 146 (7): 1714–26.e5. doi:10.1053/j.gastro.2014.03.002. PMID 24631494.
- Guo H, Wu L, Yang Q, Ye M, Zhu X (January 2015). "Functional linc-POU3F3 is overexpressed and contributes to tumorigenesis in glioma". Gene. 554 (1): 114–9. doi:10.1016/j.gene.2014.10.038. PMID 25445282.
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