PPP1R13L

RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene.[5][6]

PPP1R13L
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPPP1R13L, IASPP, NKIP1, RAI, RAI4, protein phosphatase 1 regulatory subunit 13 like
External IDsOMIM: 607463 MGI: 3525053 HomoloGene: 84635 GeneCards: PPP1R13L
Orthologs
SpeciesHumanMouse
Entrez

10848

333654

Ensembl

ENSG00000104881

ENSMUSG00000040734

UniProt

Q8WUF5

Q5I1X5

RefSeq (mRNA)

NM_006663
NM_001142502

NM_001010836

RefSeq (protein)

NP_001135974
NP_006654

NP_001010836

Location (UCSC)Chr 19: 45.38 – 45.41 MbChr 7: 19.09 – 19.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

PPP1R13L has been shown to interact with Sp1 transcription factor[7] and RELA.[5][7]

References

  1. GRCh38: Ensembl release 89: ENSG00000104881 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000040734 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Yang JP, Hori M, Sanda T, Okamoto T (May 1999). "Identification of a novel inhibitor of nuclear factor-kappaB, RelA-associated inhibitor". The Journal of Biological Chemistry. 274 (22): 15662–70. doi:10.1074/jbc.274.22.15662. PMID 10336463.
  6. "Entrez Gene: PPP1R13L protein phosphatase 1, regulatory (inhibitor) subunit 13 like".
  7. Takada N, Sanda T, Okamoto H, Yang JP, Asamitsu K, Sarol L, Kimura G, Uranishi H, Tetsuka T, Okamoto T (August 2002). "RelA-associated inhibitor blocks transcription of human immunodeficiency virus type 1 by inhibiting NF-kappaB and Sp1 actions". Journal of Virology. 76 (16): 8019–30. doi:10.1128/JVI.76.16.8019-8030.2002. PMC 155123. PMID 12134007.

Further reading

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