PREB

Prolactin regulatory element-binding protein is a protein that in humans is encoded by the PREB gene.[5][6][7]

PREB
Identifiers
AliasesPREB, SEC12, prolactin regulatory element binding
External IDsOMIM: 606395 MGI: 1355326 HomoloGene: 40877 GeneCards: PREB
Orthologs
SpeciesHumanMouse
Entrez

10113

50907

Ensembl

ENSG00000138073

ENSMUSG00000045302

UniProt

Q9HCU5

Q9WUQ2

RefSeq (mRNA)

NM_001330484
NM_001330485
NM_001330486
NM_001330487
NM_013388

NM_001294302
NM_016703

RefSeq (protein)

NP_001317413
NP_001317414
NP_001317415
NP_001317416
NP_037520

NP_001281231
NP_057912

Location (UCSC)Chr 2: 27.13 – 27.13 MbChr 5: 30.95 – 30.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.[7]

References

Further reading


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