PSRC1

Proline/serine-rich coiled-coil protein 1 is a protein that in humans is encoded by the PSRC1 gene.[5][6][7]

PSRC1
Identifiers
AliasesPSRC1, DDA3, FP3214, proline and serine rich coiled-coil 1
External IDsOMIM: 613126 MGI: 1913099 HomoloGene: 49603 GeneCards: PSRC1
Orthologs
SpeciesHumanMouse
Entrez

84722

56742

Ensembl

ENSG00000134222

ENSMUSG00000068744

UniProt

Q6PGN9
Q5T2Z0

Q9D0P7

RefSeq (mRNA)

NM_001190161
NM_019976

RefSeq (protein)

NP_001177090
NP_064360

Location (UCSC)Chr 1: 109.28 – 109.28 MbChr 3: 108.29 – 108.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a proline-rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000134222 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000068744 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lo PK, Wang FF (Nov 2002). "Cloning and characterization of human and mouse DDA3 genes". Biochim Biophys Acta. 1579 (2–3): 214–8. doi:10.1016/s0167-4781(02)00512-2. PMID 12427559.
  6. Lo PK, Chen JY, Lo WC, Chen BF, Hsin JP, Tang PP, Wang FF (Feb 2000). "Identification of a novel mouse p53 target gene DDA3". Oncogene. 18 (54): 7765–74. doi:10.1038/sj.onc.1203167. PMID 10618717.
  7. "Entrez Gene: PSRC1 proline/serine-rich coiled-coil 1".

Further reading

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