Pamabrom

Pamabrom
Clinical data
AHFS/Drugs.com	Multum Consumer Information
MedlinePlus	a681004
ATC code	none;
Legal status
Legal status	US: OTC;
Identifiers
	IUPAC name 1:1 mixture of 2-amino-2-methyl-1-propanol and 8-bromotheophyllinate;
CAS Number	606-04-2 ;
PubChem CID	11806;
ChemSpider	11313 ;
UNII	UA8U0KJM72;
ChEMBL	ChEMBL2104825 ;
CompTox Dashboard (EPA)	DTXSID80209397 ;
ECHA InfoCard	100.009.186
Chemical and physical data
Formula	8-Bromotheophylline: C7H7BrN4O2; 2-Amino-2-methyl-1-propanol: C4H11NO
Molar mass	348.20 g/mol
3D model (JSmol)	Interactive image;
	SMILES Cn2c(=O)c1[nH]c(Br)nc1n(C)c2=O.NC(C)(C)CO;
	InChI InChI=1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3 ; Key:ATOTUUBRFJHZQG-UHFFFAOYSA-N ;
	(what is this?) (verify)

Pamabrom manufactured by Chattem Chemicals, and is a product included in retail drugs available in over-the-counter medications. The active diuretic ingredient in pamabrom is 8-bromotheophylline and it also contains aminoisobutanol.

Pamabrom is available in combination with acetaminophen (paracetamol) for various conditions such as back pain and menstrual relief.[1] The acetaminophen helps reduce menstrual pains and the pamabrom reduces associated bloating. The combination is available in a number of products from various brands under different names. The dosages are essentially the same for each brand, including generic drug store varieties.

A diuretic is also used to reduce edema (fluid buildup) in the body. Edema can cause swelling of the extremities, such as in the hands and feet. Edema can make it harder the heart to work properly, and it can be related to congestive heart failure.

References

Di Girolamo G, Sánchez AJ, De Los Santos AR, González CD (March 2004). "Is acetaminophen, and its combination with pamabrom, an effective therapeutic option in primary dysmenorrhoea?". Expert Opinion on Pharmacotherapy. 5 (3): 561–70. doi:10.1517/14656566.5.3.561. PMID 15013925. S2CID 26876035.

External links

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[pmid15013925-1] Di Girolamo G, Sánchez AJ, De Los Santos AR, González CD (March 2004). "Is acetaminophen, and its combination with pamabrom, an effective therapeutic option in primary dysmenorrhoea?". Expert Opinion on Pharmacotherapy. 5 (3): 561–70. doi:10.1517/14656566.5.3.561. PMID 15013925. S2CID 26876035.