Perfluorohexyloctane

Perfluorohexyloctane, sold under the brand name Miebo is a medication used for the treatment of dry eye disease.[1] It is a semifluorinated alkane.[1]

Perfluorohexyloctane
Clinical data
Trade namesMiebo
Other namesNOV03; 1-(perfluorohexyl)octane
License data
Routes of
administration
Eye drops
ATC code
  • None
Legal status
Legal status
Identifiers
  • 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorotetradecane
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H17F13
Molar mass432.269 g·mol−1
3D model (JSmol)
  • CCCCCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
  • InChI=1S/C14H17F13/c1-2-3-4-5-6-7-8-9(15,16)10(17,18)11(19,20)12(21,22)13(23,24)14(25,26)27/h2-8H2,1H3
  • Key:WRYIIOKOQSICTB-UHFFFAOYSA-N

Perfluorohexyloctane was approved for medical use in the United States in May 2023.[1][2]

Medical uses

Perfluorohexyloctane is indicated for the treatment of the signs and symptoms of dry eye disease.[1]

References

  1. "Miebo- perfluorohexyloctane solution". DailyMed. 18 May 2023. Retrieved 8 June 2023.
  2. "Bausch + Lomb and Novaliq Announce FDA Approval of Miebo (Perfluorohexyloctane Ophthalmic Solution) for the Treatment of the Signs and Symptoms of Dry Eye Disease" (Press release). Bausch + Lomb Corporation. 18 May 2023. Retrieved 8 June 2023 via Business Wire.


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