Phytanate—CoA ligase

In enzymology, a phytanate—CoA ligase (EC 6.2.1.24) is an enzyme that catalyzes the chemical reaction

ATP + phytanate + CoA AMP + diphosphate + phytanoyl-CoA
Phytanate—CoA ligase
Identifiers
EC no.6.2.1.24
CAS no.105238-50-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

The 3 substrates of this enzyme are ATP, phytanate, and CoA, whereas its 3 products are AMP, diphosphate, and phytanoyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is phytanate:CoA ligase (AMP-forming). This enzyme is also called phytanoyl-CoA ligase.

References

    • Muralidharan FN, Muralidharan VB (1986). "Phytanoyl-CoA ligase activity in rat liver". Biochem. Int. 13 (1): 123–30. PMID 3753503.


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