Phytoene desaturase (3,4-didehydrolycopene-forming)
Phytoene desaturase (3,4-didehydrolycopene-forming) (EC 1.3.99.30, 5-step phytoene desaturase, five-step phytoene desaturase, phytoene desaturase (ambiguous), Al-1) is an enzyme with systematic name 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming).[1][2] This enzyme catalyses the following chemical reaction
- 15-cis-phytoene + 5 acceptor all-trans-3,4-didehydrolycopene + 5 reduced acceptor (overall reaction)
- (1a) 15-cis-phytoene + acceptor all-trans-phytofluene + reduced acceptor
- (1b) all-trans-phytofluene + acceptor all-trans-zeta-carotene + reduced acceptor
- (1c) all-trans-zeta-carotene + acceptor all-trans-neurosporene + reduced acceptor
- (1d) all-trans-neurosporene + acceptor all-trans-lycopene + reduced acceptor
- (1e) all-trans-lycopene + acceptor all-trans-3,4-didehydrolycopene + reduced acceptor
| Phytoene desaturase (3,4-didehydrolycopene-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.99.30 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is involved in carotenoid biosynthesis.
See also
References
- Hausmann A, Sandmann G (July 2000). "A single five-step desaturase is involved in the carotenoid biosynthesis pathway to beta-carotene and torulene in Neurospora crassa". Fungal Genetics and Biology. 30 (2): 147–53. doi:10.1006/fgbi.2000.1212. PMID 11017770.
- Estrada AF, Maier D, Scherzinger D, Avalos J, Al-Babili S (November 2008). "Novel apocarotenoid intermediates in Neurospora crassa mutants imply a new biosynthetic reaction sequence leading to neurosporaxanthin formation". Fungal Genetics and Biology. 45 (11): 1497–505. doi:10.1016/j.fgb.2008.09.001. PMID 18812228.
External links
- Phytoene+desaturase+(3,4-didehydrolycopene-forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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