Pinosylvin synthase
In enzymology, a pinosylvin synthase (EC 2.3.1.146) is an enzyme that catalyzes the chemical reaction
- 3 malonyl-CoA + cinnamoyl-CoA 4 CoA + pinosylvin + 4 CO2
| pinosylvin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.146 | ||||||||
| CAS no. | 72994-49-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are malonyl-CoA and cinnamoyl-CoA, whereas its 3 products are CoA, pinosylvin, and CO2.[1]
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing). Other names in common use include stilbene synthase, and pine stilbene synthase.[2] This enzyme participates in phenylpropanoid biosynthesis.[2]
References
- Gehlert R (1990). "Stilbene Synthase from Seedlings of Pinus sylvestris : Purification and Induction in Response to Fungal Infection". Molecular Plant-Microbe Interactions. 3 (6): 444. doi:10.1094/MPMI-3-444.
- Valletta A, Iozia LM, Leonelli F (January 2021). "Impact of Environmental Factors on Stilbene Biosynthesis". Plants. 10 (1): 90. doi:10.3390/plants10010090. PMC 7823792. PMID 33406721.
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