Protease-sparing regimen

Protease-sparing regimen, often abbreviated as PSR, is a method or therapy for treating people infected with HIV that involves a three-drug combination that reduces viral load below the limit of detection while saving protease inhibitors for later use. It is considered a weaker (in terms of quantity and concentration) form of HIV treatment. It has been argued that such a regimen is not as potent as giving HIV patients with the strongest drugs as soon as it is detected. Others believe that this might be considered a long-term strategy in order to reduce the amount of HIV,[1] and in some instances have proven to be successful.[2]

Protease-sparing regimen
Other namesPSR
Specialtyvirology

See also

References
  1. Corales RB, Shrestha NK, Taege AJ, et al. (2001). "Protease-sparing regimen in a real-life practice with naïve patients: an equal opportunity approach?". HIV Clin Trials. 2 (1): 17–21. doi:10.1310/2V0B-HDWC-AGWR-H56M. PMID 11590510. S2CID 26663673.
  2. Van der Linden D, Hainaut M, Goetghebuer T, et al. (April 2007). "Effectiveness of early initiation of protease inhibitor-sparing antiretroviral regimen in human immunodeficiency virus-1 vertically infected infants". Pediatr. Infect. Dis. J. 26 (4): 359–61. doi:10.1097/01.inf.0000258626.34984.eb. hdl:2078/119175. PMID 17414406. S2CID 74548567.
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