Prothionamide

Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis and leprosy.[1][2]

Prothionamide
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 2-propylpyridine-4-carbothioamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.034.615
Chemical and physical data
FormulaC9H12N2S
Molar mass180.27 g·mol−1
3D model (JSmol)
  • CCCc1cc(ccn1)C(=S)N
  • InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) ☒N
  • Key:VRDIULHPQTYCLN-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

References
  1. Wang F, Langley R, Gulten G, et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". J. Exp. Med. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.
  2. Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". Am. J. Trop. Med. Hyg. 74 (3): 457–61. doi:10.4269/ajtmh.2006.74.457. PMID 16525107. S2CID 21415032.
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