Putative amino acid permease family

The putative amino acid permease (PAAP) family (TC# 2.A.120) belongs to the APC superfamily.[1] The PAAP family consists of many proteins, all of a uniform topology with a 5 + 5 TMS repeat in a 2 + 3 + 2 + 3 arrangement. These proteins show similarity to members of the LIVCS family (TC# 2.A.26) in the APC Superfamily.[1][2] A representative list of recognized members of the PAAP family is available in the Transporter Classification Database.

References

  1. Vastermark, Ake; Wollwage, Simon; Houle, Michael E.; Rio, Rita; Saier, Milton H. (2014-10-01). "Expansion of the APC superfamily of secondary carriers". Proteins. 82 (10): 2797–2811. doi:10.1002/prot.24643. ISSN 1097-0134. PMC 4177346. PMID 25043943.
  2. Saier, MH Jr. "2.A.120 The Putative Amino Acid Permease (PAAP) Family". Transporter Classification Database. Saier Lab Bioinformatics Group @ UCSD / SDSC.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.