Pyridoxamine—pyruvate transaminase

In enzymology, a pyridoxamine-pyruvate transaminase (EC 2.6.1.30) is an enzyme that catalyzes the chemical reaction

pyridoxamine + pyruvate pyridoxal + L-alanine
pyridoxamine-pyruvate transaminase
Identifiers
EC no.2.6.1.30
CAS no.9023-38-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Thus, the two substrates of this enzyme are pyridoxamine and pyruvate, whereas its two products are pyridoxal and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is pyridoxamine:pyruvate aminotransferase. This enzyme is also called pyridoxamine-pyruvic transaminase. This enzyme participates in vitamin B6 metabolism.

References

    • Wada H, Snell EE (January 1962). "Enzymatic transamination of pyridoxamine. II. Crystalline pyridoxamine-pyruvate transaminase". The Journal of Biological Chemistry. 237: 133–7. PMID 14004227.


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