Pyrogallol 1,2-oxygenase
In enzymology, a pyrogallol 1,2-oxygenase (EC 1.13.11.35) is an enzyme that catalyzes the chemical reaction
- 1,2,3-trihydroxybenzene + O2 (Z)-5-oxohex-2-enedioate
| pyrogallol 1,2-oxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.11.35 | ||||||||
| CAS no. | 78310-68-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are 1,2,3-trihydroxybenzene and O2, whereas its product is (Z)-5-oxohex-2-enedioate.
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing). This enzyme is also called pyrogallol 1,2-dioxygenase.
References
- Groseclose EE, Ribbons DW (1981). "Metabolism of resorcinylic compounds by bacteria: new pathway for resorcinol catabolism in Azotobacter vinelandii". J. Bacteriol. 146 (2): 460–6. PMC 216987. PMID 7217008.
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