QIIME

QIIME (pronounced chime) is a bioinformatics data science platform, originally developed for analysis of high-throughput microbiome marker gene (e.g. 16S or 18S rRNA genes) amplicon sequencing data. There have been two major versions of the QIIME platform, QIIME 1[1] and QIIME 2.[2]

While microbiome marker gene analysis continues to be a major focus in QIIME 2, the developers describe it as a microbiome multi-omics platform, and support exists or is being added for analysis of shotgun metagenomics and metatranscriptomics data, as well as metabolomics mass spectrometry data.

Development of QIIME 1 was initiated in the Knight Lab at the University of Colorado at Boulder, and the first version of QIIME 1 was released on 26 January 2010. Beginning in August 2011, QIIME 1 development was led as a collaboration between the Caporaso Lab at Northern Arizona University and the Knight Lab. QIIME 2 development is led by the Caporaso Lab, but the project remains a community effort, with developers dispersed around the world. The hub of the QIIME 2 community is the QIIME 2 Forum.

"QIIME" was originally coined as an acronym for Quantitative Insights Into Microbial Ecology, but since the development of QIIME 2 this acronym has not been used.

See also

References
  1. Caporaso, J. Gregory; Kuczynski, Justin; Stombaugh, Jesse; Bittinger, Kyle; et al. (May 2010). "QIIME allows analysis of high-throughput community sequencing data". Nature Methods. 7 (5): 335–336. doi:10.1038/nmeth.f.303. PMC 3156573.
  2. Bolyen, Evan; Rideout, Jai Ram; Dillon, Matthew R.; Bokulich, Nicholas A.; et al. (August 2019). "Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2". Nature Biotechnology. 37 (8): 852–857. doi:10.1038/s41587-019-0209-9. hdl:1721.1/125325.
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