Quercetin-3,3'-bissulfate 7-sulfotransferase
In enzymology, a quercetin-3,3'-bissulfate 7-sulfotransferase (EC 2.8.2.28) is an enzyme that catalyzes the chemical reaction
- 3'-phosphoadenylyl sulfate + quercetin 3,3'-bissulfate adenosine 3',5'-bisphosphate + quercetin 3,7,3'-trisulfate
| quercetin-3,3'-bissulfate 7-sulfotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.2.28 | ||||||||
| CAS no. | 121855-13-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and quercetin 3,3'-bissulfate, whereas its two products are adenosine 3',5'-bisphosphate and quercetin 3,7,3'-trissulfate.
This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase. Other names in common use include flavonol 7-sulfotransferase, 7-sulfotransferase, and PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase.
References
- Varin L (1988). "Enzymatic synthesis of sulfated flavonoids in Flaveria spp". Bull. Liaison-Groupe Polyphenols. 14: 248–257.
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