RAB25

Ras-related protein Rab-25 is a protein that in humans is encoded by the RAB25 gene.[5][6] It is thought to act as a promoter of tumor development.[7]

RAB25
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRAB25, CATX-8, RAB11C, member RAS oncogene family
External IDsOMIM: 612942 MGI: 1858203 HomoloGene: 22995 GeneCards: RAB25
Orthologs
SpeciesHumanMouse
Entrez

57111

53868

Ensembl

ENSG00000132698

ENSMUSG00000008601

UniProt

P57735

Q9WTL2

RefSeq (mRNA)

NM_020387

NM_016899

RefSeq (protein)

NP_065120

NP_058595

Location (UCSC)Chr 1: 156.06 – 156.07 MbChr 3: 88.45 – 88.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

RAB25 has been shown to interact with RAB11FIP2[8][9] and RAB11FIP5.[8][9]

References

  1. GRCh38: Ensembl release 89: ENSG00000132698 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000008601 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Pereira-Leal JB, Seabra MC (November 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
  6. "Entrez Gene: RAB25 RAB25, member RAS oncogene family".
  7. Kessler, D; Gruen, GC; Heider, D; Morgner, J; Reis, H; Schmid, KW; Jendrossek, V (2012). "The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration". Cellular Physiology and Biochemistry. 29 (5–6): 647–56. doi:10.1159/000295249. PMID 22613965.
  8. Hales, C M; Griner R; Hobdy-Henderson K C; Dorn M C; Hardy D; Kumar R; Navarre J; Chan E K; Lapierre L A; Goldenring J R (October 2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. 276 (42): 39067–75. doi:10.1074/jbc.M104831200. ISSN 0021-9258. PMID 11495908.
  9. Prekeris, R; Davies J M; Scheller R H (October 2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. 276 (42): 38966–70. doi:10.1074/jbc.M106133200. ISSN 0021-9258. PMID 11481332.

Further reading


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