RBM47

RNA binding motif protein 47 is a protein in humans that is encoded by the RBM47 gene in chromosome 4. [5]

RBM47
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRBM47, NET18, RNA binding motif protein 47
External IDsMGI: 2384294 HomoloGene: 36932 GeneCards: RBM47
Orthologs
SpeciesHumanMouse
Entrez

54502

245945

Ensembl

ENSG00000163694

ENSMUSG00000070780

UniProt

A0AV96

Q91WT8

RefSeq (mRNA)

NM_001098634
NM_019027
NM_001371113
NM_001371114

NM_001127382
NM_001291226
NM_139065
NM_178446

RefSeq (protein)

NP_001092104
NP_061900
NP_001358042
NP_001358043

NP_001120854
NP_001278155
NP_620704
NP_848541

Location (UCSC)Chr 4: 40.42 – 40.63 MbChr 5: 66.17 – 66.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Model organisms

Model organisms have been used in the study of RBM47 function. A conditional knockout mouse line called Rbm47tm1a(EUCOMM)Wtsi was generated at the Wellcome Trust Sanger Institute.[6] Male and female animals underwent a standardized phenotypic screen[7] to determine the effects of deletion.[8][9][10][11] Additional screens performed: - In-depth immunological phenotyping[12]



References
  1. GRCh38: Ensembl release 89: ENSG00000163694 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000070780 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: RNA binding motif protein 47". Retrieved 2013-06-01.
  6. Gerdin AK (2010). "The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice". Acta Ophthalmologica. 88: 925–7. doi:10.1111/j.1755-3768.2010.4142.x. S2CID 85911512.
  7. "International Mouse Phenotyping Consortium".
  8. Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A (Jun 2011). "A conditional knockout resource for the genome-wide study of mouse gene function". Nature. 474 (7351): 337–42. doi:10.1038/nature10163. PMC 3572410. PMID 21677750.
  9. Dolgin E (Jun 2011). "Mouse library set to be knockout". Nature. 474 (7351): 262–3. doi:10.1038/474262a. PMID 21677718.
  10. Collins FS, Rossant J, Wurst W (Jan 2007). "A mouse for all reasons". Cell. 128 (1): 9–13. doi:10.1016/j.cell.2006.12.018. PMID 17218247. S2CID 18872015.
  11. White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, Adams NC, Sanger Institute Mouse Genetics Project, Tannahill D, Logan DW, Macarthur DG, Flint J, Mahajan VB, Tsang SH, Smyth I, Watt FM, Skarnes WC, Dougan G, Adams DJ, Ramirez-Solis R, Bradley A, Steel KP (2013). "Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes". Cell. 154 (2): 452–64. doi:10.1016/j.cell.2013.06.022. PMC 3717207. PMID 23870131.
  12. "Infection and Immunity Immunophenotyping (3i) Consortium".

Further reading


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