RFFL

E3 ubiquitin-protein ligase rififylin is an enzyme that in humans is encoded by the RFFL gene.[5][6]

RFFL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRFFL, CARP-2, CARP2, FRING, RIFIFYLIN, RNF189, RNF34L, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase, ring finger and FYVE like domain containing E3 ubiquitin protein ligase
External IDsOMIM: 609735 MGI: 1914588 HomoloGene: 12116 GeneCards: RFFL
Orthologs
SpeciesHumanMouse
Entrez

117584

67338

Ensembl

ENSG00000092871

ENSMUSG00000020696

UniProt

Q8WZ73

Q6ZQM0

RefSeq (mRNA)

NM_001017368
NM_057178

NM_001007465
NM_001164569
NM_001164570
NM_001164571
NM_026097

RefSeq (protein)

NP_001017368

NP_001007466
NP_001158041
NP_001158042
NP_001158043
NP_080373

Location (UCSC)Chr 17: 35.01 – 35.09 MbChr 11: 82.69 – 82.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000092871 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000020696 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Coumailleau F, Das V, Alcover A, Raposo G, Vandormael-Pournin S, Le Bras S, Baldacci P, Dautry-Varsat A, Babinet C, Cohen-Tannoudji M (Sep 2004). "Over-Expression of Rififylin, a New RING Finger and FYVE-like Domain-containing Protein, Inhibits Recycling from the Endocytic Recycling Compartment". Mol Biol Cell. 15 (10): 4444–56. doi:10.1091/mbc.E04-04-0274. PMC 519139. PMID 15229288.
  6. "Entrez Gene: RFFL ring finger and FYVE-like domain containing 1".

Further reading


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